Terms: = Leukemia AND MAP2K2, MEK2, 5605, ENSG00000126934, P36507, MKK2, MAPKK2, PRKMK2 AND Treatment
10 results:
1. CLDN4 promotes growth of acute myeloid leukemia cells via regulating AKT and ERK1/2 signaling.
Hao S; Yang C; Song P; Shi H; Zou Y; Chen M; Wu X; Yin Y; Yu Z; Zhu W; Li M
Biochem Biophys Res Commun; 2022 Sep; 619():137-143. PubMed ID: 35760010
[TBL] [Abstract] [Full Text] [Related]
2. Activity of the oral mitogen-activated protein kinase kinase inhibitor trametinib in RAS-mutant relapsed or refractory myeloid malignancies.
Borthakur G; Popplewell L; Boyiadzis M; Foran J; Platzbecker U; Vey N; Walter RB; Olin R; Raza A; Giagounidis A; Al-Kali A; Jabbour E; Kadia T; Garcia-Manero G; Bauman JW; Wu Y; Liu Y; Schramek D; Cox DS; Wissel P; Kantarjian H
Cancer; 2016 Jun; 122(12):1871-9. PubMed ID: 26990290
[TBL] [Abstract] [Full Text] [Related]
3. MAPK signaling cascades mediate distinct glucocorticoid resistance mechanisms in pediatric leukemia.
Jones CL; Gearheart CM; Fosmire S; Delgado-Martin C; Evensen NA; Bride K; Waanders AJ; Pais F; Wang J; Bhatla T; Bitterman DS; de Rijk SR; Bourgeois W; Dandekar S; Park E; Burleson TM; Madhusoodhan PP; Teachey DT; Raetz EA; Hermiston ML; Müschen M; Loh ML; Hunger SP; Zhang J; Garabedian MJ; Porter CC; Carroll WL
Blood; 2015 Nov; 126(19):2202-12. PubMed ID: 26324703
[TBL] [Abstract] [Full Text] [Related]
4. Copper is required for oncogenic BRAF signalling and tumorigenesis.
Brady DC; Crowe MS; Turski ML; Hobbs GA; Yao X; Chaikuad A; Knapp S; Xiao K; Campbell SL; Thiele DJ; Counter CM
Nature; 2014 May; 509(7501):492-6. PubMed ID: 24717435
[TBL] [Abstract] [Full Text] [Related]
5. Trametinib: first global approval.
Wright CJ; McCormack PL
Drugs; 2013 Jul; 73(11):1245-54. PubMed ID: 23846731
[TBL] [Abstract] [Full Text] [Related]
6. Selumetinib-enhanced radioiodine uptake in advanced thyroid cancer.
Ho AL; Grewal RK; Leboeuf R; Sherman EJ; Pfister DG; Deandreis D; Pentlow KS; Zanzonico PB; Haque S; Gavane S; Ghossein RA; Ricarte-Filho JC; DomÃnguez JM; Shen R; Tuttle RM; Larson SM; Fagin JA
N Engl J Med; 2013 Feb; 368(7):623-32. PubMed ID: 23406027
[TBL] [Abstract] [Full Text] [Related]
7. EphB receptors trigger Akt activation and suppress Fas receptor-induced apoptosis in malignant T lymphocytes.
Maddigan A; Truitt L; Arsenault R; Freywald T; Allonby O; Dean J; Narendran A; Xiang J; Weng A; Napper S; Freywald A
J Immunol; 2011 Dec; 187(11):5983-94. PubMed ID: 22039307
[TBL] [Abstract] [Full Text] [Related]
8. The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells.
Longo PG; Laurenti L; Gobessi S; Sica S; Leone G; Efremov DG
Blood; 2008 Jan; 111(2):846-55. PubMed ID: 17928528
[TBL] [Abstract] [Full Text] [Related]
9. Respiratory syncytial virus inhibits granulocyte apoptosis through a phosphatidylinositol 3-kinase and NF-kappaB-dependent mechanism.
Lindemans CA; Coffer PJ; Schellens IM; de Graaff PM; Kimpen JL; Koenderman L
J Immunol; 2006 May; 176(9):5529-37. PubMed ID: 16622022
[TBL] [Abstract] [Full Text] [Related]
10. Importance of MEK-1/-2 signaling in monocytic and granulocytic differentiation of myeloid cell lines.
Miranda MB; McGuire TF; Johnson DE
Leukemia; 2002 Apr; 16(4):683-92. PubMed ID: 11960350
[TBL] [Abstract] [Full Text] [Related]
