BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND MAP2K4, MEK4, 6416, P45985, ENSG00000065559, SERK1, JNKK1, MKK4, PRKMK4, MAPKK4, JNKK, SEK1 AND Treatment
13 results:

  • 1. Molecular and oral manifestations of langerhans cell histiocytosis preceding acute myeloid leukemia.
    Zhang Q; Wu X; Wang X; Pan E; Ying L
    BMC Oral Health; 2022 Sep; 22(1):386. PubMed ID: 36064398
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Huai Qi Huang-induced Apoptosis via Down-regulating PRKCH and Inhibiting RAF/MEK/ERK Pathway in Ph
    Xu WF; Wang ZJ; Li K; Shen YQ; Lu K; Lv XY; Wen YX; Jin RM
    Curr Med Sci; 2020 Apr; 40(2):354-362. PubMed ID: 32337697
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. MAPK signaling cascades mediate distinct glucocorticoid resistance mechanisms in pediatric leukemia.
    Jones CL; Gearheart CM; Fosmire S; Delgado-Martin C; Evensen NA; Bride K; Waanders AJ; Pais F; Wang J; Bhatla T; Bitterman DS; de Rijk SR; Bourgeois W; Dandekar S; Park E; Burleson TM; Madhusoodhan PP; Teachey DT; Raetz EA; Hermiston ML; Müschen M; Loh ML; Hunger SP; Zhang J; Garabedian MJ; Porter CC; Carroll WL
    Blood; 2015 Nov; 126(19):2202-12. PubMed ID: 26324703
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. MCL-1 degradation mediated by JNK activation via MEKK1/TAK1-mkk4 contributes to anticancer activity of new tubulin inhibitor MT189.
    Wang W; Wang YQ; Meng T; Yi JM; Huan XJ; Ma LP; Tong LJ; Chen Y; Ding J; Shen JK; Miao ZH
    Mol Cancer Ther; 2014 Jun; 13(6):1480-91. PubMed ID: 24688049
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Withanolide D induces apoptosis in leukemia by targeting the activation of neutral sphingomyelinase-ceramide cascade mediated by synergistic activation of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase.
    Mondal S; Mandal C; Sangwan R; Chandra S; Mandal C
    Mol Cancer; 2010 Sep; 9():239. PubMed ID: 20836852
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Antimony trioxide-induced apoptosis is dependent on sek1/JNK signaling.
    Mann KK; Davison K; Colombo M; Colosimo AL; Diaz Z; Padovani AM; Guo Q; Scrivens PJ; Gao W; Mader S; Miller WH
    Toxicol Lett; 2006 Jan; 160(2):158-70. PubMed ID: 16112521
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Farnesyltransferase inhibitors interact synergistically with the Chk1 inhibitor UCN-01 to induce apoptosis in human leukemia cells through interruption of both Akt and MEK/ERK pathways and activation of sek1/JNK.
    Dai Y; Rahmani M; Pei XY; Khanna P; Han SI; Mitchell C; Dent P; Grant S
    Blood; 2005 Feb; 105(4):1706-16. PubMed ID: 15494423
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Bortezomib and flavopiridol interact synergistically to induce apoptosis in chronic myeloid leukemia cells resistant to imatinib mesylate through both Bcr/Abl-dependent and -independent mechanisms.
    Dai Y; Rahmani M; Pei XY; Dent P; Grant S
    Blood; 2004 Jul; 104(2):509-18. PubMed ID: 15039284
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. JNK activation is a mediator of arsenic trioxide-induced apoptosis in acute promyelocytic leukemia cells.
    Davison K; Mann KK; Waxman S; Miller WH
    Blood; 2004 May; 103(9):3496-502. PubMed ID: 14701702
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Implication of raft microdomains in drug induced apoptosis.
    Bezombes C; Laurent G; Jaffrézou JP
    Curr Med Chem Anticancer Agents; 2003 Jul; 3(4):263-70. PubMed ID: 12769772
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. [Echocardiographic assessment of circulation system in patients during and 3-5 years after all therapy in childhood].
    Ostański M; Sońta-Jakimczyk D
    Wiad Lek; 2002; 55(3-4):164-73. PubMed ID: 12182001
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. [Exercise tolerance in patients after acute lymphoblastic leukemia treatment in childhood].
    Ostański M; Sońta-Jakimczyk D
    Wiad Lek; 2001; 54(11-12):650-5. PubMed ID: 11928552
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Functional role for protein kinase Cbeta as a regulator of stress-activated protein kinase activation and monocytic differentiation of myeloid leukemia cells.
    Kaneki M; Kharbanda S; Pandey P; Yoshida K; Takekawa M; Liou JR; Stone R; Kufe D
    Mol Cell Biol; 1999 Jan; 19(1):461-70. PubMed ID: 9858570
    [TBL] [Abstract] [Full Text] [Related]  


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