BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND MED12, Q93074, TRAP230, TNRC11, OKS, KIAA0192, HOPA, FGS1, CAGH45, ARC240, 9968
23 results:

  • 1. Enhancer-activated RET confers protection against oxidative stress to KMT2A-rearranged acute myeloid leukemia.
    Frett B; Stephens KE; Koss B; Melnyk S; Farrar J; Saha D; Roy Choudhury S
    Cancer Sci; 2024 Mar; 115(3):963-973. PubMed ID: 38226414
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. The protein landscape of chronic lymphocytic leukemia.
    Meier-Abt F; Lu J; Cannizzaro E; Pohly MF; Kummer S; Pfammatter S; Kunz L; Collins BC; Nadeu F; Lee KS; Xue P; Gwerder M; Roiss M; Hüllein J; Scheinost S; Dietrich S; Campo E; Huber W; Aebersold R; Zenz T
    Blood; 2021 Dec; 138(24):2514-2525. PubMed ID: 34189564
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Epigenetic analysis reveals significant differential expression of miR-378C and miR-128-2-5p in a cohort of relapsed pediatric B-acute lymphoblastic leukemia cases.
    Bhatia P; Singh M; Singh A; Sharma P; Trehan A; Varma N
    Int J Lab Hematol; 2021 Oct; 43(5):1016-1023. PubMed ID: 33538126
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Clonal dynamics in a composite chronic lymphocytic leukemia and hairy cell leukemia-variant.
    Locher M; Jukic E; Bohn JP; Untergasser G; Steurer M; Cramer CA; Schwendinger S; Vogi V; Verdorfer I; Witsch-Baumgartner M; Nachbaur D; Gunsilius E; Wolf D; Zschocke J; Steiner N
    Genes Chromosomes Cancer; 2021 Apr; 60(4):287-292. PubMed ID: 33277788
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Predictive significance of selected gene mutations in relapsed and refractory chronic lymphocytic leukemia patients treated with ibrutinib.
    Machnicki MM; Górniak P; Pępek M; Szymczyk A; Iskierka-Jażdżewska E; Steckiewicz P; Bluszcz A; Rydzanicz M; Hus M; Płoski R; Makuch-Łasica H; Nowak G; Juszczyński P; Jamroziak K; Stokłosa T; Puła B
    Eur J Haematol; 2021 Mar; 106(3):320-326. PubMed ID: 33190294
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Initial steps in reconstruction of the human ovary: survival of pre-antral stage follicles in a decellularized human ovarian scaffold.
    Pors SE; Ramløse M; Nikiforov D; Lundsgaard K; Cheng J; Andersen CY; Kristensen SG
    Hum Reprod; 2019 Aug; 34(8):1523-1535. PubMed ID: 31286144
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Complex karyotype in de novo acute myeloid leukemia: typical and atypical subtypes differ molecularly and clinically.
    Mrózek K; Eisfeld AK; Kohlschmidt J; Carroll AJ; Walker CJ; Nicolet D; Blachly JS; Bill M; Papaioannou D; Wang ES; Uy GL; Kolitz JE; Powell BL; Blum W; Stone RM; Byrd JC; Bloomfield CD
    Leukemia; 2019 Jul; 33(7):1620-1634. PubMed ID: 30737482
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Factors targeting
    Bullerdiek J; Rommel B
    F1000Res; 2018; 7():359. PubMed ID: 30647905
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Modified enzyme multiplied immunoassay technique of methotrexate assay to improve sensitivity and reduce cost.
    Shi X; Gao H; Li Z; Li J; Liu Y; Li L; Zhang Q
    BMC Pharmacol Toxicol; 2019 Jan; 20(1):3. PubMed ID: 30626430
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Single-cell sequencing reveals the origin and the order of mutation acquisition in T-cell acute lymphoblastic leukemia.
    De Bie J; Demeyer S; Alberti-Servera L; Geerdens E; Segers H; Broux M; De Keersmaecker K; Michaux L; Vandenberghe P; Voet T; Boeckx N; Uyttebroeck A; Cools J
    Leukemia; 2018 Jun; 32(6):1358-1369. PubMed ID: 29740158
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Novel Richter Syndrome Xenograft Models to Study Genetic Architecture, Biology, and Therapy Responses.
    Vaisitti T; Braggio E; Allan JN; Arruga F; Serra S; Zamò A; Tam W; Chadburn A; Furman RR; Deaglio S
    Cancer Res; 2018 Jul; 78(13):3413-3420. PubMed ID: 29735551
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Oncogenic exon 2 mutations in Mediator subunit med12 disrupt allosteric activation of cyclin C-CDK8/19.
    Park MJ; Shen H; Spaeth JM; Tolvanen JH; Failor C; Knudtson JF; McLaughlin J; Halder SK; Yang Q; Bulun SE; Al-Hendy A; Schenken RS; Aaltonen LA; Boyer TG
    J Biol Chem; 2018 Mar; 293(13):4870-4882. PubMed ID: 29440396
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. med12 mutations and NOTCH signalling in chronic lymphocytic leukaemia.
    Wu B; Słabicki M; Sellner L; Dietrich S; Liu X; Jethwa A; Hüllein J; Walther T; Wagner L; Huang Z; Zapatka M; Zenz T
    Br J Haematol; 2017 Nov; 179(3):421-429. PubMed ID: 28771672
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Panel oks CAR T Therapy for leukemia.
    Cancer Discov; 2017 Sep; 7(9):924. PubMed ID: 28751490
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Somatic med12 Nonsense Mutation Escapes mRNA Decay and Reveals a Motif Required for Nuclear Entry.
    Heikkinen T; Kämpjärvi K; Keskitalo S; von Nandelstadh P; Liu X; Rantanen V; Pitkänen E; Kinnunen M; Kuusanmäki H; Kontro M; Turunen M; Mäkinen N; Taipale J; Heckman C; Lehti K; Mustjoki S; Varjosalo M; Vahteristo P
    Hum Mutat; 2017 Mar; 38(3):269-274. PubMed ID: 28054750
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Genomic Profile of Chronic Lymphocytic leukemia in Korea Identified by Targeted Sequencing.
    Kim JA; Hwang B; Park SN; Huh S; Im K; Choi S; Chung HY; Huh J; Seo EJ; Lee JH; Bang D; Lee DS
    PLoS One; 2016; 11(12):e0167641. PubMed ID: 27959900
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Genomic characterization of pediatric T-cell acute lymphoblastic leukemia reveals novel recurrent driver mutations.
    Spinella JF; Cassart P; Richer C; Saillour V; Ouimet M; Langlois S; St-Onge P; Sontag T; Healy J; Minden MD; Sinnett D
    Oncotarget; 2016 Oct; 7(40):65485-65503. PubMed ID: 27602765
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Suppression of BCL2 by Antisense Oligonucleotides and Compensation by Non-Targeted Genes May Enhance Tumor Proliferation.
    Rubenstein M; Hollowell CM; Guinan P
    In Vivo; 2015; 29(6):687-93. PubMed ID: 26546525
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Presence of multiple recurrent mutations confers poor trial outcome of relapsed/refractory CLL.
    Guièze R; Robbe P; Clifford R; de Guibert S; Pereira B; Timbs A; Dilhuydy MS; Cabes M; Ysebaert L; Burns A; Nguyen-Khac F; Davi F; Véronèse L; Combes P; Le Garff-Tavernier M; Leblond V; Merle-Béral H; Alsolami R; Hamblin A; Mason J; Pettitt A; Hillmen P; Taylor J; Knight SJ; Tournilhac O; Schuh A
    Blood; 2015 Oct; 126(18):2110-7. PubMed ID: 26316624
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Somatic med12 mutations are associated with poor prognosis markers in chronic lymphocytic leukemia.
    Kämpjärvi K; Järvinen TM; Heikkinen T; Ruppert AS; Senter L; Hoag KW; Dufva O; Kontro M; Rassenti L; Hertlein E; Kipps TJ; Porkka K; Byrd JC; de la Chapelle A; Vahteristo P
    Oncotarget; 2015 Jan; 6(3):1884-8. PubMed ID: 25595892
    [TBL] [Abstract] [Full Text] [Related]  


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