Terms: = Leukemia AND MLLT1, ENL, 4298, ENSG00000130382, Q03111, YEATS1, LTG19 AND Prognosis
40 results:
1. A complex interplay of intra- and extracellular factors regulates the outcome of fetal- and adult-derived MLL-rearranged leukemia.
Jassinskaja M; Ghosh S; Watral J; Davoudi M; Claesson Stern M; Daher U; Eldeeb M; Zhang Q; Bryder D; Hansson J
Leukemia; 2024 May; 38(5):1115-1130. PubMed ID: 38555405
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2. Bahcc1 is critical for the aberrant epigenetic program in a mouse model of MLL-enl-mediated leukemia.
Nakamura A; Masuya M; Shinmei M; Tawara I; Nosaka T; Ono R
Blood Adv; 2024 May; 8(9):2193-2206. PubMed ID: 38452334
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3. A fetal tumor suppressor axis abrogates MLL-fusion-driven acute myeloid leukemia.
Eldeeb M; Yuan O; Guzzi N; Thi Ngoc PC; Konturek-Ciesla A; Kristiansen TA; Muthukumar S; Magee J; Bellodi C; Yuan J; Bryder D
Cell Rep; 2023 Feb; 42(2):112099. PubMed ID: 36763502
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4. Prognostic value and outcome for acute lymphocytic leukemia in children with MLL rearrangement: a case-control study.
Qiu KY; Zhou DH; Liao XY; Huang K; Li Y; Xu HG; Weng WJ; Xu LH; Fang JP
BMC Cancer; 2022 Dec; 22(1):1257. PubMed ID: 36461002
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5. Small-Molecule Inhibition of the Acyl-Lysine Reader enl as a Strategy against Acute Myeloid leukemia.
Liu Y; Li Q; Alikarami F; Barrett DR; Mahdavi L; Li H; Tang S; Khan TA; Michino M; Hill C; Song L; Yang L; Li Y; Pokharel SP; Stamford AW; Liverton N; Renzetti LM; Taylor S; Watt GF; Ladduwahetty T; Kargman S; Meinke PT; Foley MA; Shi J; Li H; Carroll M; Chen CW; Gardini A; Maillard I; Huggins DJ; Bernt KM; Wan L
Cancer Discov; 2022 Nov; 12(11):2684-2709. PubMed ID: 36053276
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6. Multi-omics analysis defines highly refractory RAS burdened immature subgroup of infant acute lymphoblastic leukemia.
Isobe T; Takagi M; Sato-Otsubo A; Nishimura A; Nagae G; Yamagishi C; Tamura M; Tanaka Y; Asada S; Takeda R; Tsuchiya A; Wang X; Yoshida K; Nannya Y; Ueno H; Akazawa R; Kato I; Mikami T; Watanabe K; Sekiguchi M; Seki M; Kimura S; Hiwatari M; Kato M; Fukuda S; Tatsuno K; Tsutsumi S; Kanai A; Inaba T; Shiozawa Y; Shiraishi Y; Chiba K; Tanaka H; Kotecha RS; Cruickshank MN; Ishikawa F; Morio T; Eguchi M; Deguchi T; Kiyokawa N; Arakawa Y; Koh K; Aoki Y; Ishihara T; Tomizawa D; Miyamura T; Ishii E; Mizutani S; Wilson NK; Göttgens B; Miyano S; Kitamura T; Goyama S; Yokoyama A; Aburatani H; Ogawa S; Takita J
Nat Commun; 2022 Aug; 13(1):4501. PubMed ID: 36042201
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7. Poor treatment responses were related to poor outcomes in pediatric B cell acute lymphoblastic leukemia with KMT2A rearrangements.
Wen J; Zhou M; Shen Y; Long Y; Guo Y; Song L; Xiao J
BMC Cancer; 2022 Aug; 22(1):859. PubMed ID: 35933338
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8. KMT2A-mllt1 and the Novel SEC16A-KMT2A in a Cryptic 3-Way Translocation t(9;11;19) Present in an Infant With Acute Lymphoblastic leukemia.
de Matos RRC; Ferreira GM; Meyer C; Marschalek R; Larghero P; Ribeiro RC; Liehr T; Othman M; Bizarro MTSM; Sobral da Costa E; Land MGP; Abdelhay E; Binato R; Silva MLM
J Pediatr Hematol Oncol; 2022 Apr; 44(3):e719-e722. PubMed ID: 34966090
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9. KAT6A and enl Form an Epigenetic Transcriptional Control Module to Drive Critical Leukemogenic Gene-Expression Programs.
Yan F; Li J; Milosevic J; Petroni R; Liu S; Shi Z; Yuan S; Reynaga JM; Qi Y; Rico J; Yu S; Liu Y; Rokudai S; Palmisiano N; Meyer SE; Sung PJ; Wan L; Lan F; Garcia BA; Stanger BZ; Sykes DB; Blanco MA
Cancer Discov; 2022 Mar; 12(3):792-811. PubMed ID: 34853079
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10. Molecular regulators of HOXA9 in acute myeloid leukemia.
Aryal S; Zhang Y; Wren S; Li C; Lu R
FEBS J; 2023 Jan; 290(2):321-339. PubMed ID: 34743404
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11. Nuclear FGFR2 Interacts with the MLL-AF4 Oncogenic Chimera and Positively Regulates
Fioretti T; Cevenini A; Zanobio M; Raia M; Sarnataro D; Cattaneo F; Ammendola R; Esposito G
Int J Mol Sci; 2021 Apr; 22(9):. PubMed ID: 33924850
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12. Structure, function and inhibition of critical protein-protein interactions involving mixed lineage leukemia 1 and its fusion oncoproteins.
Li X; Song Y
J Hematol Oncol; 2021 Apr; 14(1):56. PubMed ID: 33823889
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13. First report of t(5;11) KMT2A-MAML1 fusion in de novo infant acute lymphoblastic leukemia.
Tandon S; Shago M; Davidson S; Kanwar N; Fuligni F; Shlien A; Whitlock J; Villani A; Abla O
Cancer Genet; 2020 Oct; 248-249():31-33. PubMed ID: 32992102
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14. Fusion partner-specific mutation profiles and KRAS mutations as adverse prognostic factors in MLL-rearranged AML.
Matsuo H; Yoshida K; Nakatani K; Harata Y; Higashitani M; Ito Y; Kamikubo Y; Shiozawa Y; Shiraishi Y; Chiba K; Tanaka H; Okada A; Nannya Y; Takeda J; Ueno H; Kiyokawa N; Tomizawa D; Taga T; Tawa A; Miyano S; Meggendorfer M; Haferlach C; Ogawa S; Adachi S
Blood Adv; 2020 Oct; 4(19):4623-4631. PubMed ID: 32991719
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15. Exploitable metabolic dependencies in MLL-enl-induced leukemia.
Garcia-Cuellar MP; Lawlor J; Böttcher M; Mougiakakos D; Metzler M; Slany RK
Blood Adv; 2020 Aug; 4(15):3626-3638. PubMed ID: 32766858
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16. Development of embryonic and adult leukemia mouse models driven by MLL-enl translocation.
Sinha R; Porcheri C; d'Altri T; González J; Ruiz-Herguido C; Rabbitts T; Espinosa L; Bigas A
Exp Hematol; 2020 May; 85():13-19. PubMed ID: 32437911
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17. MLL-Rearranged Acute Lymphoblastic leukemia.
El Chaer F; Keng M; Ballen KK
Curr Hematol Malig Rep; 2020 Apr; 15(2):83-89. PubMed ID: 32350732
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18. Increased Risk of Acute Myelogenous leukemia After Early Onset but Not Late-Onset Colorectal Cancer.
Lehrer S; Rheinstein PH
Am J Clin Oncol; 2020 Apr; 43(4):263-269. PubMed ID: 31876540
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19. A New Complex Karyotype Involving a KMT2A-r Variant Three-Way Translocation in a Rare Clinical Presentation of a Pediatric Patient with Acute Myeloid leukemia.
Capela de Matos RR; Ney Garcia DR; Othman MAK; Moura Ferreira G; Melo JB; Carreira IM; Meyer C; Marschalek R; Costa ES; Land MGP; Liehr T; Ribeiro RC; Silva MLM
Cytogenet Genome Res; 2019; 157(4):213-219. PubMed ID: 30974445
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20. The Incidence and Immunophenotypic and Genetic Features of JL1 Expressing Cells and the Therapeutic Potential of an Anti-JL1 Antibody in
Park SH; You E; Park CJ; Jang S; Cho YU; Yoon CH; Koh KN; Im HJ; Seo JJ
Ann Lab Med; 2019 Jul; 39(4):358-366. PubMed ID: 30809981
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