BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND MLLT10, P55197, 8028, ENSG00000078403, AF10 AND Treatment
34 results:

  • 1. Application of droplet digital PCR in minimal residual disease monitoring of rare fusion transcripts and mutations in haematological malignancies.
    Ip BBK; Wong ATC; Law JHY; Au CH; Ma SY; Chim JCS; Liang RHS; Leung AYH; Wan TSK; Ma ESK
    Sci Rep; 2024 Mar; 14(1):6400. PubMed ID: 38493200
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. treatment outcomes of childhood PICALM::mllt10 acute leukaemias.
    Mark C; Meshinchi S; Joyce B; Gibson B; Harrison C; Bergmann AK; Goemans BF; Pronk CJH; Lapillonne H; Leverger G; Antoniou E; Schneider M; Attarbaschi A; Dworzak M; Stary J; Tomizawa D; Ebert S; Lejman M; Kolb EA; Schmiegelow K; Hasle H; Abla O
    Br J Haematol; 2024 Feb; 204(2):576-584. PubMed ID: 37743097
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Etiology of oncogenic fusions in 5,190 childhood cancers and its clinical and therapeutic implication.
    Liu Y; Klein J; Bajpai R; Dong L; Tran Q; Kolekar P; Smith JL; Ries RE; Huang BJ; Wang YC; Alonzo TA; Tian L; Mulder HL; Shaw TI; Ma J; Walsh MP; Song G; Westover T; Autry RJ; Gout AM; Wheeler DA; Wan S; Wu G; Yang JJ; Evans WE; Loh M; Easton J; Zhang J; Klco JM; Meshinchi S; Brown PA; Pruett-Miller SM; Ma X
    Nat Commun; 2023 Apr; 14(1):1739. PubMed ID: 37019972
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Retrospective Study of Three Cases of Congenital leukemia with Clinical Presentations and Particular Cytogenetic Abnormality.
    Yang R; Chi C; Chen J; Lv Z; Wang J; Huang H; Guo W; Zhou X; Liu L; Li Q
    Clin Lab; 2022 Jun; 68(6):. PubMed ID: 35704725
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Clinico-biological features of T-cell acute lymphoblastic leukemia with fusion proteins.
    Steimlé T; Dourthe ME; Alcantara M; Touzart A; Simonin M; Mondesir J; Lhermitte L; Bond J; Graux C; Grardel N; Cayuela JM; Arnoux I; Gandemer V; Balsat M; Vey N; Macintyre E; Ifrah N; Dombret H; Petit A; Baruchel A; Ruminy P; Boissel N; Asnafi V
    Blood Cancer J; 2022 Jan; 12(1):14. PubMed ID: 35082269
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. [Analysis of Clinical Characteristics and Prognosis in Children with Acute Megakaryoblastic leukemia without Down Syndrome].
    Lin SF; Guo SY; Liu S; Wang J; Huang K; Li Y; Fang JP; Zhou DH
    Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2021 Apr; 29(2):374-380. PubMed ID: 33812402
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Fusion partner-specific mutation profiles and KRAS mutations as adverse prognostic factors in MLL-rearranged AML.
    Matsuo H; Yoshida K; Nakatani K; Harata Y; Higashitani M; Ito Y; Kamikubo Y; Shiozawa Y; Shiraishi Y; Chiba K; Tanaka H; Okada A; Nannya Y; Takeda J; Ueno H; Kiyokawa N; Tomizawa D; Taga T; Tawa A; Miyano S; Meggendorfer M; Haferlach C; Ogawa S; Adachi S
    Blood Adv; 2020 Oct; 4(19):4623-4631. PubMed ID: 32991719
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Failure of tofacitinib to achieve an objective response in a
    Wong J; Wall M; Corboy GP; Taubenheim N; Gregory GP; Opat S; Shortt J
    Cold Spring Harb Mol Case Stud; 2020 Aug; 6(4):. PubMed ID: 32843425
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction.
    Somers K; Wen VW; Middlemiss SMC; Osborne B; Forgham H; Jung M; Karsa M; Clifton M; Bongers A; Gao J; Mayoh C; Raoufi-Rad N; Kusnadi EP; Hannan KM; Scott DA; Kwek A; Liu B; Flemming C; Chudakova DA; Pandher R; Failes TW; Lim J; Angeli A; Osterman AL; Imamura T; Kees UR; Supuran CT; Pearson RB; Hannan RD; Davis TP; McCarroll J; Kavallaris M; Turner N; Gudkov AV; Haber M; Norris MD; Henderson MJ
    Oncogene; 2019 May; 38(20):3824-3842. PubMed ID: 30670779
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. [Characteristics and prognosis in adult acute myeloid leukemia patients with MLL gene rearrangements].
    Gong XY; Wang Y; Liu BC; Wei H; Li CW; Li QH; Zhao JW; Zhou CL; Lin D; Liu KQ; Wei SN; Gong BF; Zhang GJ; Liu YT; Zhao XL; Li Y; Gu RX; Qiu SW; Mi YC; Wang JX
    Zhonghua Xue Ye Xue Za Zhi; 2018 Jan; 39(1):9-14. PubMed ID: 29551026
    [No Abstract]    [Full Text] [Related]  

  • 11. Successful treatment of a Very Late Isolated Relapse in an Adolescent With a PICALM-mllt10 Positive T-lineage Acute Lymphoblastic leukemia.
    Cannata E; Samperi P; Cimino C; Marino S; Sullo F; Mirabile E; Di Cataldo A; Russo G; Lo Nigro L
    J Pediatr Hematol Oncol; 2018 Apr; 40(3):e191-e194. PubMed ID: 29189509
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Cooperative gene activation by AF4 and DOT1L drives MLL-rearranged leukemia.
    Okuda H; Stanojevic B; Kanai A; Kawamura T; Takahashi S; Matsui H; Takaori-Kondo A; Yokoyama A
    J Clin Invest; 2017 May; 127(5):1918-1931. PubMed ID: 28394257
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. [Biological microchip for establishing the structure of fusion transcripts involving MLL in children with acute leukemia].
    Nasedkina TV; Ikonnikova AY; Tsaur GA; Karateeva AV; Ammour YI; Avdonina MA; Karachunskii AI; Zasedatelev AS
    Mol Biol (Mosk); 2016; 50(6):968-977. PubMed ID: 28064313
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Cooperation of MLL/af10(OM-LZ) with PTPN11 activating mutation induced monocytic leukemia with a shorter latency in a mouse bone marrow transplantation model.
    Fu JF; Liang ST; Huang YJ; Liang KH; Yen TH; Liang DC; Shih LY
    Int J Cancer; 2017 Mar; 140(5):1159-1172. PubMed ID: 27859216
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. CCI-007, a novel small molecule with cytotoxic activity against infant leukemia with MLL rearrangements.
    Somers K; Chudakova DA; Middlemiss SM; Wen VW; Clifton M; Kwek A; Liu B; Mayoh C; Bongers A; Karsa M; Pan S; Cruikshank S; Scandlyn M; Hoang W; Imamura T; Kees UR; Gudkov AV; Chernova OB; Haber M; Norris MD; Henderson MJ
    Oncotarget; 2016 Jul; 7(29):46067-46087. PubMed ID: 27317766
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. MLL leukemia and future treatment strategies.
    Marschalek R
    Arch Pharm (Weinheim); 2015 Apr; 348(4):221-8. PubMed ID: 25740345
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. mllt10 and IL3 rearrangement together with a complex four-way translocation and trisomy 4 in a patient with early T-cell precursor acute lymphoblastic leukemia: A case report.
    Othman MA; Melo JB; Carreira IM; Rincic M; Alhourani E; Wilhelm K; Gruhn B; Glaser A; Liehr T
    Oncol Rep; 2015 Feb; 33(2):625-30. PubMed ID: 25435396
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Complex MLL rearrangement in non-infiltrated bone marrow in an infant with stage II precursor B-lymphoblastic lymphoma.
    Ahlmann M; Meyer C; Marschalek R; Burkhardt B; Koehler G; Klapper W; Juergens H; Rossig C
    Eur J Haematol; 2014 Oct; 93(4):349-53. PubMed ID: 24635731
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. [Application of multiplex nested RT- PCR assay for screening the fusion genes in acute myeloid leukemia and its clinical significance].
    Xu Y; Gao L; Sun J; Ding Y; Xu Y; Lyu C; Liu W; Wang N; Wang L; Yu L
    Zhonghua Xue Ye Xue Za Zhi; 2014 Jan; 35(1):29-34. PubMed ID: 24602728
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. The prognosis of CALM-af10-positive adult T-cell acute lymphoblastic leukemias depends on the stage of maturation arrest.
    Ben Abdelali R; Asnafi V; Petit A; Micol JB; Callens C; Villarese P; Delabesse E; Reman O; Lepretre S; Cahn JY; Guillerm G; Berthon C; Gardin C; Corront B; Leguay T; Béné MC; Ifrah N; Leverger G; Dombret H; Macintyre E
    Haematologica; 2013 Nov; 98(11):1711-7. PubMed ID: 23831922
    [TBL] [Abstract] [Full Text] [Related]  


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