BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND MTOR, FRAP2, FRAP1, 2475, ENSG00000198793, P42345, RAPT1, RAFT1, FRAP, FLJ44809 AND Clinical Outcome
11 results:

  • 1. Poricoic acid A (PAA) inhibits T-cell acute lymphoblastic leukemia through inducing autophagic cell death and ferroptosis.
    Chen L; Fang W; Liu J; Qi X; Zhao L; Wang Y; Liu Y; Kong D; Sun X; Li X; Sha Q; Sun G
    Biochem Biophys Res Commun; 2022 Jun; 608():108-115. PubMed ID: 35397422
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. NTAL is associated with treatment outcome, cell proliferation and differentiation in acute promyelocytic leukemia.
    Thomé CH; Ferreira GA; Pereira-Martins DA; Dos Santos GA; Ortiz CA; de Souza LEB; Sobral LM; Silva CLA; Scheucher PS; Gil CD; Leopoldino AM; Silveira DRA; Coelho-Silva JL; Traina F; Koury LC; Melo RAM; Bittencourt R; Pagnano K; Pasquini R; Nunes EC; Fagundes EM; Gloria ABF; Kerbauy FR; Chauffaille ML; Keating A; Tallman MS; Ribeiro RC; Dillon R; Ganser A; Löwenberg B; Valk P; Lo-Coco F; Sanz MA; Berliner N; Faça VM; Rego EM
    Sci Rep; 2020 Jun; 10(1):10315. PubMed ID: 32587277
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Downregulation of MCL-1 and upregulation of PUMA using mtor inhibitors enhance antitumor efficacy of BH3 mimetics in triple-negative breast cancer.
    Li H; Liu L; Chang H; Zou Z; Xing D
    Cell Death Dis; 2018 Jan; 9(2):137. PubMed ID: 29374168
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. High mtor expression independently prognosticates poor clinical outcome to induction chemotherapy in acute lymphoblastic leukemia.
    Khanna A; Bhushan B; Chauhan PS; Saxena S; Gupta DK; Siraj F
    Clin Exp Med; 2018 May; 18(2):221-227. PubMed ID: 29076004
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic leukemia: A Genome Sequencing Study.
    Li Y; Buijs-Gladdines JG; Canté-Barrett K; Stubbs AP; Vroegindeweij EM; Smits WK; van Marion R; Dinjens WN; Horstmann M; Kuiper RP; Buijsman RC; Zaman GJ; van der Spek PJ; Pieters R; Meijerink JP
    PLoS Med; 2016 Dec; 13(12):e1002200. PubMed ID: 27997540
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Metformin synergistically sensitizes FLT3-ITD-positive acute myeloid leukemia to sorafenib by promoting mtor-mediated apoptosis and autophagy.
    Wang F; Liu Z; Zeng J; Zhu H; Li J; Cheng X; Jiang T; Zhang L; Zhang C; Chen T; Liu T; Jia Y
    Leuk Res; 2015 Dec; 39(12):1421-7. PubMed ID: 26505133
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Inhibition of 32Dp210 cells harboring T315I mutation by a novel derivative of emodin correlates with down-regulation of BCR-ABL and its downstream signaling pathways.
    Li J; Chen Y; Chen B; Chen C; Qiu B; Zheng Z; Zheng J; Liu T; Wang W; Hu J
    J Cancer Res Clin Oncol; 2015 Feb; 141(2):283-93. PubMed ID: 25217883
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Histone deacetylase inhibitor potentiated the ability of mtor inhibitor to induce autophagic cell death in Burkitt leukemia/lymphoma.
    Dong LH; Cheng S; Zheng Z; Wang L; Shen Y; Shen ZX; Chen SJ; Zhao WL
    J Hematol Oncol; 2013 Jul; 6():53. PubMed ID: 23866964
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. A pathobiological role of the insulin receptor in chronic lymphocytic leukemia.
    Saiya-Cork K; Collins R; Parkin B; Ouillette P; Kuizon E; Kujawski L; Erba H; Campagnaro E; Shedden K; Kaminski M; Malek SN
    Clin Cancer Res; 2011 May; 17(9):2679-92. PubMed ID: 21307146
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Targeted therapies in gynecologic cancers.
    Chon HS; Hu W; Kavanagh JJ
    Curr Cancer Drug Targets; 2006 Jun; 6(4):333-63. PubMed ID: 16848724
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Transcriptional profiles in peripheral blood mononuclear cells prognostic of clinical outcomes in patients with advanced renal cell carcinoma.
    Burczynski ME; Twine NC; Dukart G; Marshall B; Hidalgo M; Stadler WM; Logan T; Dutcher J; Hudes G; Trepicchio WL; Strahs A; Immermann F; Slonim DK; Dorner AJ
    Clin Cancer Res; 2005 Feb; 11(3):1181-9. PubMed ID: 15709187
    [TBL] [Abstract] [Full Text] [Related]  


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