BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND PTCH1, RP11-435O5_3, Q13635, PTCH, 5727, HPE7, FLJ26746, NBCCS, BCNS, PTC1, ENSG00000185920, FLJ42602 AND Treatment
17 results:

  • 1. Sustained Suppression of Gorlin Syndrome-Associated Basal Cell Carcinomas with Vismodegib or Sonidegib: A Case Series.
    Wescott R; Samlowski W
    Curr Oncol; 2023 Oct; 30(10):9156-9167. PubMed ID: 37887561
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. Prevalence of pathogenic variants in cancer-predisposing genes in second cancer after childhood solid cancers.
    Yoshida M; Nakabayashi K; Yang W; Sato-Otsubo A; Tsujimoto SI; Ogata-Kawata H; Kawai T; Ishiwata K; Sakamoto M; Okamura K; Yoshida K; Shirai R; Osumi T; Kiyotani C; Shioda Y; Terashima K; Ishimaru S; Yuza Y; Takagi M; Arakawa Y; Imamura T; Hasegawa D; Inoue A; Yoshioka T; Ito S; Tomizawa D; Koh K; Matsumoto K; Kiyokawa N; Ogawa S; Manabe A; Niwa A; Hata K; Yang JJ; Kato M
    Cancer Med; 2023 May; 12(10):11264-11273. PubMed ID: 37021926
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Prediction of optimal cytogenetic responses at 6 and 12 months in patients with chronic myeloid leukemia in chronic phase treated with imatinib.
    Milosevic V; Jovanovic MP; Bukumirić Z; Djordjevic V; Jovanovic J; Fekete MD; Lekovic D; Bogdanovic A
    J BUON; 2021; 26(3):1070-1079. PubMed ID: 34268974
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. A Gli inhibitor GANT61 suppresses cell proliferation, promotes cell apoptosis and induces G1/G0 cycle retardation with a dose- and time-dependent manner through inhibiting Notch pathway in multiple myeloma.
    Zhang Z; Hao C; Zhang R; Pei X; Li J; Wang L
    Cell Cycle; 2020 Aug; 19(16):2063-2073. PubMed ID: 32677544
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Genomic testing, tumor microenvironment and targeted therapy of Hedgehog-related human cancers.
    Katoh M
    Clin Sci (Lond); 2019 Apr; 133(8):953-970. PubMed ID: 31036756
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Targeting Hedgehog (Hh) Pathway for the Acute Myeloid leukemia treatment.
    Terao T; Minami Y
    Cells; 2019 Apr; 8(4):. PubMed ID: 30987263
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. A novel hedgehog inhibitor for the treatment of hematological malignancies.
    Lin P; He Y; Chen G; Ma H; Zheng J; Zhang Z; Cao B; Zhang H; Zhang X; Mao X
    Anticancer Drugs; 2018 Nov; 29(10):995-1003. PubMed ID: 30106753
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. SHH desmoplastic/nodular medulloblastoma and Gorlin syndrome in the setting of Down syndrome: case report, molecular profiling, and review of the literature.
    Mangum R; Varga E; Boué DR; Capper D; Benesch M; Leonard J; Osorio DS; Pierson CR; Zumberge N; Sahm F; Schrimpf D; Pfister SM; Finlay JL
    Childs Nerv Syst; 2016 Dec; 32(12):2439-2446. PubMed ID: 27444290
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Pyrazolopyrimidine Derivatives as Antineoplastic Agents: with a Special Focus on Thyroid Cancer.
    Ferrari SM; La Motta C; Sartini S; Baldini E; Materazzi G; Politti U; Ruffilli I; Ulisse S; Miccoli P; Antonelli A; Fallahi P
    Mini Rev Med Chem; 2016; 16(2):86-93. PubMed ID: 26471970
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. The Hedgehog pathway: role in cell differentiation, polarity and proliferation.
    Jia Y; Wang Y; Xie J
    Arch Toxicol; 2015 Feb; 89(2):179-91. PubMed ID: 25559776
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Arsenic trioxide prevents osteosarcoma growth by inhibition of GLI transcription via DNA damage accumulation.
    Nakamura S; Nagano S; Nagao H; Ishidou Y; Yokouchi M; Abematsu M; Yamamoto T; Komiya S; Setoguchi T
    PLoS One; 2013; 8(7):e69466. PubMed ID: 23861973
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Tracking molecular relapse of chronic myeloid leukemia by measuring Hedgehog signaling status.
    Cea M; Cagnetta A; Cirmena G; Garuti A; Rocco I; Palermo C; Pierri I; Reverberi D; Nencioni A; Ballestrero A; Gobbi M; Carella AM; Patrone F
    Leuk Lymphoma; 2013 Feb; 54(2):342-52. PubMed ID: 22762548
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Sonic hedgehog signaling regulates Bcr-Abl expression in human chronic myeloid leukemia cells.
    Liao HF; Su YC; Zheng ZY; Jhih Cai C; Hou MH; Chao KS; Chen YJ
    Biomed Pharmacother; 2012 Jul; 66(5):378-83. PubMed ID: 22397755
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. Trisomy 12 and elevated GLI1 and ptch1 transcript levels are biomarkers for Hedgehog-inhibitor responsiveness in CLL.
    Decker S; Zirlik K; Djebatchie L; Hartmann D; Ihorst G; Schmitt-Graeff A; Herchenbach D; Jumaa H; Warmuth M; Veelken H; Dierks C
    Blood; 2012 Jan; 119(4):997-1007. PubMed ID: 22130798
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Activation of the Hedgehog pathway in chronic myelogeneous leukemia patients.
    Long B; Zhu H; Zhu C; Liu T; Meng W
    J Exp Clin Cancer Res; 2011 Jan; 30(1):8. PubMed ID: 21235817
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Targeting of sonic hedgehog-GLI signaling: a potential strategy to improve therapy for mantle cell lymphoma.
    Hegde GV; Munger CM; Emanuel K; Joshi AD; Greiner TC; Weisenburger DD; Vose JM; Joshi SS
    Mol Cancer Ther; 2008 Jun; 7(6):1450-60. PubMed ID: 18524848
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Methylation profiling in acute myeloid leukemia.
    Toyota M; Kopecky KJ; Toyota MO; Jair KW; Willman CL; Issa JP
    Blood; 2001 May; 97(9):2823-9. PubMed ID: 11313277
    [TBL] [Abstract] [Full Text] [Related]  


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