Terms: = Leukemia AND RAC1, ENSG00000136238, 5879, MIG5, MGC111543, P63000, p21-Rac1, TC-25 AND Prognosis
10 results:
1. CKS1 inhibition depletes leukemic stem cells and protects healthy hematopoietic stem cells in acute myeloid leukemia.
Grey W; Rio-Machin A; Casado P; Grönroos E; Ali S; Miettinen JJ; Bewicke-Copley F; Parsons A; Heckman CA; Swanton C; Cutillas PR; Gribben J; Fitzgibbon J; Bonnet D
Sci Transl Med; 2022 Jun; 14(650):eabn3248. PubMed ID: 35731890
[TBL] [Abstract] [Full Text] [Related]
2. Actin cytoskeleton deregulation confers midostaurin resistance in FLT3-mutant acute myeloid leukemia.
Garitano-Trojaola A; Sancho A; Götz R; Eiring P; Walz S; Jetani H; Gil-Pulido J; Da Via MC; Teufel E; Rhodes N; Haertle L; Arellano-Viera E; Tibes R; Rosenwald A; Rasche L; Hudecek M; Sauer M; Groll J; Einsele H; Kraus S; Kortüm MK
Commun Biol; 2021 Jun; 4(1):799. PubMed ID: 34172833
[TBL] [Abstract] [Full Text] [Related]
3. Integrative Network Analysis of Differentially Methylated and Expressed Genes for Biomarker Identification in leukemia.
Sanchez R; Mackenzie SA
Sci Rep; 2020 Feb; 10(1):2123. PubMed ID: 32034170
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4. FLT3-ITD cooperates with rac1 to modulate the sensitivity of leukemic cells to chemotherapeutic agents via regulation of DNA repair pathways.
Wu M; Li L; Hamaker M; Small D; Duffield AS
Haematologica; 2019 Dec; 104(12):2418-2428. PubMed ID: 30975911
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5. Wnt5a and ROR1 activate non-canonical Wnt signaling via RhoA in TCF3-PBX1 acute lymphoblastic leukemia and highlight new treatment strategies via Bcl-2 co-targeting.
Karvonen H; Perttilä R; Niininen W; Hautanen V; Barker H; Murumägi A; Heckman CA; Ungureanu D
Oncogene; 2019 Apr; 38(17):3288-3300. PubMed ID: 30631148
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6. NUP214-rac1 and rac1-COL12A1 Fusion in Complex Variant Translocations Involving Chromosomes 6, 7 and 9 in an Acute Myeloid leukemia Case with DEK-NUP214.
Abe A; Yamamoto Y; Iba S; Okamoto A; Tokuda M; Inaguma Y; Yanada M; Morishima S; Kanie T; Tsuzuki M; Akatsuka Y; Mizuta S; Okamoto M; Kameyama T; Mayeda A; Emi N
Cytogenet Genome Res; 2015; 146(4):279-84. PubMed ID: 26517539
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7. A ROS-Activatable Agent Elicits Homologous Recombination DNA Repair and Synergizes with Pathway Compounds.
Thowfeik FS; AbdulSalam SF; Wunderlich M; Wyder M; Greis KD; Kadekaro AL; Mulloy JC; Merino EJ
Chembiochem; 2015 Nov; 16(17):2513-21. PubMed ID: 26419938
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8. Pak and Rac GTPases promote oncogenic KIT-induced neoplasms.
Martin H; Mali RS; Ma P; Chatterjee A; Ramdas B; Sims E; Munugalavadla V; Ghosh J; Mattingly RR; Visconte V; Tiu RV; Vlaar CP; Dharmawardhane S; Kapur R
J Clin Invest; 2013 Oct; 123(10):4449-63. PubMed ID: 24091327
[TBL] [Abstract] [Full Text] [Related]
9. Comparative analysis of normal versus CLL B-lymphocytes reveals patient-specific variability in signaling mechanisms controlling LFA-1 activation by chemokines.
Montresor A; Bolomini-Vittori M; Simon SI; Rigo A; Vinante F; Laudanna C
Cancer Res; 2009 Dec; 69(24):9281-90. PubMed ID: 19934331
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10. Internal tandem duplication of FLT3 (FLT3/ITD) induces increased ROS production, DNA damage, and misrepair: implications for poor prognosis in AML.
Sallmyr A; Fan J; Datta K; Kim KT; Grosu D; Shapiro P; Small D; Rassool F
Blood; 2008 Mar; 111(6):3173-82. PubMed ID: 18192505
[TBL] [Abstract] [Full Text] [Related]
