BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Leukemia AND RAF1, Raf-1, 5894, P04049, ENSG00000132155, c-Raf, CRAF AND Treatment
98 results:

  • 1. Design, Synthesis, and Anti-Leukemic Evaluation of a Series of Dianilinopyrimidines by Regulating the Ras/Raf/MEK/ERK and STAT3/c-Myc Pathways.
    Wang C; Wang B; Mou Y; Liu X; Chen Q; Pu W; Rao Q; Wang C; Song J; Huang Y; Yan L; Huang L; Li Y
    Molecules; 2024 Apr; 29(7):. PubMed ID: 38611876
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. CALGB 80802 (Alliance): Impact of Sorafenib with and without Doxorubicin on Hepatitis C Infection in Patients with Advanced Hepatocellular Carcinoma.
    Abou-Alfa GK; Geyer SM; Nixon AB; Innocenti F; Shi Q; Kumthekar P; Jacobson S; El Dika I; Yaqubie A; Lopez J; Huang B; Tang YW; Wen Y; Schwartz LH; El-Khoueiry AB; Knox JJ; Rajdev L; Bertagnolli MM; Meyerhardt JA; O'Reilly EM; Venook AP
    Cancer Res Commun; 2024 Mar; 4(3):682-690. PubMed ID: 38363156
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Exosomal circRNA-001264 promotes AML immunosuppression through induction of M2-like macrophages and PD-L1 overexpression.
    Du A; Yang Q; Sun X; Zhao Q
    Int Immunopharmacol; 2023 Nov; 124(Pt A):110868. PubMed ID: 37657244
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. Capitalizing on paradoxical activation of the mitogen-activated protein kinase pathway for treatment of Imatinib-resistant mast cell leukemia.
    Wilhelm T; Toledo MAS; Simons I; Stuth C; Mohta V; Mülfarth R; Nitsche M; Maschke-Neuß K; Schmitz S; Kaiser A; Panse J; Christen D; Arock M; Zenke M; Huber M
    Hematol Oncol; 2023 Aug; 41(3):520-534. PubMed ID: 36383121
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Phloretin Alleviates Arsenic Trioxide-Induced Apoptosis of H9c2 Cardiomyoblasts via Downregulation in Ca
    Vadavanath Prabhakaran V; Kozhiparambil Gopalan R
    Cardiovasc Toxicol; 2021 Aug; 21(8):642-654. PubMed ID: 34037972
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Curcumin promotes cell cycle arrest and apoptosis of acute myeloid leukemia cells by inactivating AKT.
    Zhou H; Ning Y; Zeng G; Zhou C; Ding X
    Oncol Rep; 2021 Apr; 45(4):. PubMed ID: 33649826
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Targetable BRAF and raf1 Alterations in Advanced Pediatric Cancers.
    Rankin A; Johnson A; Roos A; Kannan G; Knipstein J; Britt N; Rosenzweig M; Haberberger J; Pavlick D; Severson E; Vergilio JA; Squillace R; Erlich R; Sathyan P; Cramer S; Kram D; Ross J; Miller V; Reddy P; Alexander B; Ali SM; Ramkissoon S
    Oncologist; 2021 Jan; 26(1):e153-e163. PubMed ID: 32918774
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. All-Trans Retinoic Acid Synergizes with Enasidenib to Induce Differentiation of IDH2-Mutant Acute Myeloid leukemia Cells.
    Kim Y; Jeung HK; Cheong JW; Song J; Bae SH; Lee JI; Min YH
    Yonsei Med J; 2020 Sep; 61(9):762-773. PubMed ID: 32882760
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Huai Qi Huang-induced Apoptosis via Down-regulating PRKCH and Inhibiting RAF/MEK/ERK Pathway in Ph
    Xu WF; Wang ZJ; Li K; Shen YQ; Lu K; Lv XY; Wen YX; Jin RM
    Curr Med Sci; 2020 Apr; 40(2):354-362. PubMed ID: 32337697
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Tomatidine Alleviates Osteoporosis by Downregulation of p53.
    Yu T; Wu Q; You X; Zhou H; Xu S; He W; Li Z; Li B; Xia J; Zhu H; Zhao Y; Yang Y; Chen K
    Med Sci Monit; 2020 Apr; 26():e923996. PubMed ID: 32300098
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Dissecting the novel partners of nuclear c-raf and its role in all-trans retinoic acid (ATRA)-induced myeloblastic leukemia cells differentiation.
    Rashid A; Wang R; Zhang L; Yue J; Yang M; Yen A
    Exp Cell Res; 2020 Sep; 394(1):111989. PubMed ID: 32283065
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Roscovitine enhances All-trans retinoic acid (ATRA)-induced leukemia cell differentiation: Novel effects on signaling molecules for a putative Cdk2 inhibitor.
    Rashid A; Duan X; Gao F; Yang M; Yen A
    Cell Signal; 2020 Jul; 71():109555. PubMed ID: 32032659
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Nilotinib interferes with cell cycle, ABC transporters and JAK-STAT signaling pathway in CD34+/lin- cells of patients with chronic phase chronic myeloid leukemia after 12 months of treatment.
    Trojani A; Pungolino E; Dal Molin A; Lodola M; Rossi G; D'Adda M; Perego A; Elena C; Turrini M; Borin L; Bucelli C; Malato S; Carraro MC; Spina F; Latargia ML; Artale S; Spedini P; Anghilieri M; Di Camillo B; Baruzzo G; De Canal G; Iurlo A; Morra E; Cairoli R
    PLoS One; 2019; 14(7):e0218444. PubMed ID: 31318870
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. The combination of UCN-01 and ATRA triggers differentiation in ATRA resistant acute promyelocytic leukemia cell lines via raf-1 independent activation of MEK/ERK.
    Liang C; Ding M; Weng XQ; Sheng Y; Wu J; Cai X
    Food Chem Toxicol; 2019 Apr; 126():303-312. PubMed ID: 30840849
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Inhibition of the raf-1 kinase inhibitory protein (RKIP) by locostatin induces cell death and reduces the CXCR4-mediated migration of chronic lymphocytic leukemia cells.
    Crassini K; Pyke T; Shen Y; Stevenson WS; Christopherson RI; Mulligan SP; Best OG
    Leuk Lymphoma; 2018 Dec; 59(12):2917-2928. PubMed ID: 29911936
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. MEK1/2 inhibition by binimetinib is effective as a single agent and potentiates the actions of Venetoclax and ABT-737 under conditions that mimic the chronic lymphocytic leukaemia (CLL) tumour microenvironment.
    Crassini K; Shen Y; Stevenson WS; Christopherson R; Ward C; Mulligan SP; Best OG
    Br J Haematol; 2018 Aug; 182(3):360-372. PubMed ID: 29767411
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Src family kinase inhibitor bosutinib enhances retinoic acid-induced differentiation of HL-60 leukemia cells.
    MacDonald RJ; Bunaciu RP; Ip V; Dai D; Tran D; Varner JD; Yen A
    Leuk Lymphoma; 2018 Dec; 59(12):2941-2951. PubMed ID: 29569971
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Identification of gene expression models for laryngeal squamous cell carcinoma using co-expression network analysis.
    Yang CW; Wang SF; Yang XL; Wang L; Niu L; Liu JX
    Medicine (Baltimore); 2018 Feb; 97(7):e9738. PubMed ID: 29443735
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Wogonoside induces depalmitoylation and translocation of PLSCR1 and N-RAS in primary acute myeloid leukaemia cells.
    Li H; Yu X; Liu X; Hu P; Shen L; Zhou Y; Zhu Y; Li Z; Hui H; Guo Q; Xu J
    J Cell Mol Med; 2018 Apr; 22(4):2117-2130. PubMed ID: 29377576
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Dasatinib synergizes with ATRA to trigger granulocytic differentiation in ATRA resistant acute promyelocytic leukemia cell lines via Lyn inhibition-mediated activation of raf-1/MEK/ERK.
    Ding M; Weng XQ; Sheng Y; Wu J; Liang C; Cai X
    Food Chem Toxicol; 2018 Sep; 119():464-478. PubMed ID: 29097117
    [TBL] [Abstract] [Full Text] [Related]  


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