Terms: = Leukemia AND STAT5B, STAT5, 6777, ENSG00000173757, P51692 AND Treatment
364 results:
1. Ponatinib and stat5 Inhibitor Pimozide Combined Synergistic treatment Applications Potentially Overcome Drug Resistance via Regulating the Cytokine Expressional Network in Chronic Myeloid leukemia Cells.
Tezcanli Kaymaz B; Gumus N; Celik B; Alcitepe İ; Biray Avci C; Aktan C
J Interferon Cytokine Res; 2024 Apr; 44(4):178-189. PubMed ID: 38579140
[TBL] [Abstract] [Full Text] [Related]
2. IDH2/R140Q mutation confers cytokine-independent proliferation of TF-1 cells by activating constitutive STAT3/5 phosphorylation.
Yang J; Chen J; Chang J; Sun X; Wei Q; Cai X; Cao P
Cell Commun Signal; 2024 Feb; 22(1):116. PubMed ID: 38347540
[TBL] [Abstract] [Full Text] [Related]
3. The novel TERF2::PDGFRB fusion gene enhances tumorigenesis via PDGFRB/stat5 signalling pathways and sensitivity to TKI in ph-like ALL.
Xu GF; Zeng Z; Zhang ZB; Zhang XM; Wang M; Xiao Q; Li J; Xie XQ; He S; Fu HH; Liu Y; Yang ZL; Chen Y; Shi J; Wang B; Qiu HY; Zhou Q; Liu Y; Chen SN
J Cell Mol Med; 2024 Feb; 28(3):e18114. PubMed ID: 38323741
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4. Pim Kinase Inhibitors Increase Gilteritinib Cytotoxicity in FLT3-ITD Acute Myeloid leukemia Through GSK-3β Activation and c-Myc and Mcl-1 Proteasomal Degradation.
Lee JK; Chatterjee A; Scarpa M; Bailey CM; Niyongere S; Singh P; Mustafa Ali MK; Kapoor S; Wang Y; Silvestri G; Baer MR
Cancer Res Commun; 2024 Feb; 4(2):431-445. PubMed ID: 38284896
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5. Discovery of novel and potent CDK8 inhibitors for the treatment of acute myeloid leukaemia.
Chen Z; Wang Q; Yan YY; Jin D; Wang Y; Zhang XX; Liu XH
J Enzyme Inhib Med Chem; 2024 Dec; 39(1):2305852. PubMed ID: 38258519
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6. Distinct roles of hematopoietic cytokines in the regulation of leukemia stem cells in murine MLL-AF9 leukemia.
Li Y; Seet CS; Mack R; Joshi K; Runde AP; Hagen PA; Barton K; Breslin P; Kini A; Ji HL; Zhang J
Stem Cell Reports; 2024 Jan; 19(1):100-111. PubMed ID: 38101400
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7. DNMTs-mediated SOCS3 methylation promotes the occurrence and development of AML.
Zhang X; Zhang K; Zhang J; Chang W; Zhao Y; Suo X
Eur J Haematol; 2024 Mar; 112(3):439-449. PubMed ID: 37950514
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8. Targeting of stat5 using the small molecule topotecan hydrochloride suppresses acute myeloid leukemia progression.
Li J; Tang B; Miao Y; Li G; Sun Z
Oncol Rep; 2023 Dec; 50(6):. PubMed ID: 37830151
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9. stat5 promotes PD-L1 expression by facilitating histone lactylation to drive immunosuppression in acute myeloid leukemia.
Huang ZW; Zhang XN; Zhang L; Liu LL; Zhang JW; Sun YX; Xu JQ; Liu Q; Long ZJ
Signal Transduct Target Ther; 2023 Sep; 8(1):391. PubMed ID: 37777506
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10. [Large granular lymphocytic leukemia and its association with immune dysregulation].
Ishida F
Rinsho Ketsueki; 2023; 64(8):791-798. PubMed ID: 37673632
[TBL] [Abstract] [Full Text] [Related]
11. Dual inhibition of STAT3 and stat5 may overcome imatinib resistance in chronic myeloid leukemia.
Yin L; Xu J; Wu W; Niu M; Li Z; Zhu F; Xu K
Hematology; 2023 Dec; 28(1):2224625. PubMed ID: 37345979
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12. stat5b gain-of-function disease in a child with mycobacterial osteomyelitis of the skull: rare presentation of an emerging disease entity.
Kobets AJ; Ahmad S; Boyke A; Oriko D; Holland R; Eisenberg R; Alavi SAN; Abbott R
Childs Nerv Syst; 2023 Aug; 39(8):2071-2077. PubMed ID: 37243811
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13. Venetoclax-Resistant T-ALL Cells Display Distinct Cancer Stem Cell Signatures and Enrichment of Cytokine Signaling.
Shah K; Al Ashiri L; Nasimian A; Ahmed M; Kazi JU
Int J Mol Sci; 2023 Mar; 24(5):. PubMed ID: 36902436
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14. Discovery of a novel oral type Ⅰ CDK8 inhibitor against acute myeloid leukemia.
Zhang XX; Yan YY; Ma X; Xiao Y; Lei CC; Wang YM; Liu C; Wang Q; Zhang XT; Cheng WD; Liu XH
Eur J Med Chem; 2023 May; 251():115214. PubMed ID: 36889252
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15. Identification of Hub Genes Associated with Resistance to Prednisolone in Acute Lymphoblastic leukemia Based on Weighted Gene Co-expression Network Analysis.
Nekoeian S; Ferdowsian S; Asgari Y; Azizi Z
Mol Biotechnol; 2023 Nov; 65(11):1913-1922. PubMed ID: 36877306
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16. Not all LGL leukemias are created equal.
Semenzato G; Calabretto G; Barilà G; Gasparini VR; Teramo A; Zambello R
Blood Rev; 2023 Jul; 60():101058. PubMed ID: 36870881
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17. Induction of DNMT1-dependent demethylation of SHP-1 by the natural flavonoid compound Baicalein overcame Imatinib-resistance in CML CD34
Xu X; Ji S; Chen Y; Xia S; Li Y; Chen L; Li Y; Zhang F; Zhang Z; Zheng S
Cell Commun Signal; 2023 Mar; 21(1):47. PubMed ID: 36869331
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18. Targeting Proliferation Signals and the Cell Cycle Machinery in Acute leukemias: Novel Molecules on the Horizon.
Ghelli Luserna di Rorà A; Jandoubi M; Martinelli G; Simonetti G
Molecules; 2023 Jan; 28(3):. PubMed ID: 36770891
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19. Dihydropyrimidinase-like 2 can serve as a novel therapeutic target and prognostic biomarker in acute myeloid leukemia.
Li F; Ling Q; Lian J; Chen Y; Hu C; Yang M; Zhang X; Li C; Mao S; Ye W; Li X; Lin X; Wei W; Huang X; Pan J; Qian Y; Wang J; Lu Y; Jin J
Cancer Med; 2023 Apr; 12(7):8319-8330. PubMed ID: 36621846
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20. TSLP as a Potential Therapy in the treatment of CRLF2 B Cell Acute Lymphoblastic leukemia.
Alkashgari HR; Ruiz-Jimenez C; Stoian C; Coats JS; Baez I; Chirshev E; Martinez SR; Dovat S; Francis-Boyle OL; Casiano CA; Payne KJ
Int J Mol Sci; 2022 Dec; 24(1):. PubMed ID: 36613920
[TBL] [Abstract] [Full Text] [Related]
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