Terms: = Leukemia AND STK11, LKB1, 6794, ENSG00000118046, Q15831, PJS AND Treatment
11 results:
1. STAT3/lkb1 controls metastatic prostate cancer by regulating mTORC1/CREB pathway.
Pencik J; Philippe C; Schlederer M; Atas E; Pecoraro M; Grund-Gröschke S; Li WJ; Tracz A; Heidegger I; Lagger S; Trachtová K; Oberhuber M; Heitzer E; Aksoy O; Neubauer HA; Wingelhofer B; Orlova A; Witzeneder N; Dillinger T; Redl E; Greiner G; D'Andrea D; Östman JR; Tangermann S; Hermanova I; Schäfer G; Sternberg F; Pohl EE; Sternberg C; Varady A; Horvath J; Stoiber D; Malcolm TI; Turner SD; Parkes EE; Hantusch B; Egger G; Rose-John S; Poli V; Jain S; Armstrong CWD; Hoermann G; Goffin V; Aberger F; Moriggl R; Carracedo A; McKinney C; Kennedy RD; Klocker H; Speicher MR; Tang DG; Moazzami AA; Heery DM; Hacker M; Kenner L
Mol Cancer; 2023 Aug; 22(1):133. PubMed ID: 37573301
[TBL] [Abstract] [Full Text] [Related]
2. Can molecular insights guide treatment of AML evolved from MPNs?
Crispino J; Rampal R
Best Pract Res Clin Haematol; 2021 Dec; 34(4):101323. PubMed ID: 34865695
[TBL] [Abstract] [Full Text] [Related]
3. Enhanced Vulnerability of lkb1-Deficient NSCLC to Disruption of ATP Pools and Redox Homeostasis by 8-Cl-Ado.
Galan-Cobo A; Stellrecht CM; Yilmaz E; Yang C; Qian Y; Qu X; Akhter I; Ayres ML; Fan Y; Tong P; Diao L; Ding J; Giri U; Gudikote J; Nilsson M; Wierda WG; Wang J; Skoulidis F; Minna JD; Gandhi V; Heymach JV
Mol Cancer Res; 2022 Feb; 20(2):280-292. PubMed ID: 34654720
[TBL] [Abstract] [Full Text] [Related]
4. Mitochondrial dysfunction regulates the JAK-STAT pathway via lkb1-mediated AMPK activation ER-stress-independent manner.
Kim DY; Lim SG; Suk K; Lee WH
Biochem Cell Biol; 2020 Apr; 98(2):137-144. PubMed ID: 31071273
[TBL] [Abstract] [Full Text] [Related]
5. EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition.
Zucal C; D'Agostino VG; Casini A; Mantelli B; Thongon N; Soncini D; Caffa I; Cea M; Ballestrero A; Quattrone A; Indraccolo S; Nencioni A; Provenzani A
BMC Cancer; 2015 Nov; 15():855. PubMed ID: 26542945
[TBL] [Abstract] [Full Text] [Related]
6. Negative regulation of the lkb1/AMPK pathway by ERK in human acute myeloid leukemia cells.
Kawashima I; Mitsumori T; Nozaki Y; Yamamoto T; Shobu-Sueki Y; Nakajima K; Kirito K
Exp Hematol; 2015 Jul; 43(7):524-33.e1. PubMed ID: 25846811
[TBL] [Abstract] [Full Text] [Related]
7. Detection of an activated JAK3 variant and a Xq26.3 microdeletion causing loss of PHF6 and miR-424 expression in myelodysplastic syndromes by combined targeted next generation sequencing and SNP array analysis.
Kunze K; Gamerdinger U; Leßig-Owlanj J; Sorokina M; Brobeil A; Tur MK; Blau W; Burchardt A; Käbisch A; Schliesser G; Kiehl M; Rosenwald A; Rummel M; Grimminger F; Hain T; Chakraborty T; Bräuninger A; Gattenlöhner S
Pathol Res Pract; 2014 Jun; 210(6):369-76. PubMed ID: 24674452
[TBL] [Abstract] [Full Text] [Related]
8. lkb1 tumor suppressor and salt-inducible kinases negatively regulate human T-cell leukemia virus type 1 transcription.
Tang HM; Gao WW; Chan CP; Siu YT; Wong CM; Kok KH; Ching YP; Takemori H; Jin DY
Retrovirology; 2013 Apr; 10():40. PubMed ID: 23577667
[TBL] [Abstract] [Full Text] [Related]
9. Metformin and cancer.
Vallianou NG; Evangelopoulos A; Kazazis C
Rev Diabet Stud; 2013; 10(4):228-35. PubMed ID: 24841876
[TBL] [Abstract] [Full Text] [Related]
10. Targeting the liver kinase B1/AMP-activated protein kinase pathway as a therapeutic strategy for hematological malignancies.
Martelli AM; Chiarini F; Evangelisti C; Ognibene A; Bressanin D; Billi AM; Manzoli L; Cappellini A; McCubrey JA
Expert Opin Ther Targets; 2012 Jul; 16(7):729-42. PubMed ID: 22686561
[TBL] [Abstract] [Full Text] [Related]
11. The lkb1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation.
Green AS; Chapuis N; Maciel TT; Willems L; Lambert M; Arnoult C; Boyer O; Bardet V; Park S; Foretz M; Viollet B; Ifrah N; Dreyfus F; Hermine O; Moura IC; Lacombe C; Mayeux P; Bouscary D; Tamburini J
Blood; 2010 Nov; 116(20):4262-73. PubMed ID: 20668229
[TBL] [Abstract] [Full Text] [Related]
