Terms: = Leukemia AND U2AF1, ENSG00000160201, 7307, Q01081, U2AFBP, U2AF35, RNU2AF1, RN, FP793, DKFZp313J1712
234 results:
1. Biological relevance of alternative splicing in hematologic malignancies.
Szelest M; Giannopoulos K
Mol Med; 2024 May; 30(1):62. PubMed ID: 38760666
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2. Differential prognostic values of the three AKT isoforms in acute myeloid leukemia.
Corre E; Soum C; Pfeifer R; Bessière C; Dailhau S; Marbœuf C; Meggetto F; Touriol C; Récher C; Bousquet M; Pyronnet S
Sci Rep; 2024 Mar; 14(1):7070. PubMed ID: 38528080
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3. Molecular and clinical analyses of PHF6 mutant myeloid neoplasia provide their pathogenesis and therapeutic targeting.
Kubota Y; Gu X; Terkawi L; Bodo J; Przychodzen BP; Awada H; Williams N; Gurnari C; Kawashima N; Aly M; Durmaz A; Mori M; Ponvilawan B; Kewan T; Bahaj W; Meggendorfer M; Jha BK; Visconte V; Rogers HJ; Haferlach T; Maciejewski JP
Nat Commun; 2024 Feb; 15(1):1832. PubMed ID: 38418452
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4. Mutant u2af1-Induced Mis-Splicing of mRNA Translation Genes Confers Resistance to Chemotherapy in Acute Myeloid leukemia.
Jin P; Wang X; Jin Q; Zhang Y; Shen J; Jiang G; Zhu H; Zhao M; Wang D; Li Z; Zhou Y; Li W; Zhang W; Liu Y; Wang S; Jin W; Cao Y; Sheng G; Dong F; Wu S; Li X; Jin Z; He M; Liu X; Chen L; Zhang Y; Wang K; Li J
Cancer Res; 2024 May; 84(10):1583-1596. PubMed ID: 38417135
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5. [The Correlation of Gene Mutation and Clinical Characteristics in Patients with Myelodysplastic Syndrome and Prognostic Analysis].
Zhang WW; Zhang YL; Ren CC; Wu TK; Liu B
Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2024 Feb; 32(1):176-183. PubMed ID: 38387918
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6. CEBPA double mutations associated with ABO antigen weakness in hematologic diseases.
Choi SJ; Kim HK; Suh EJ; Kwon SS; Shin S; Lee ST; Kim S
Blood Adv; 2024 Mar; 8(6):1487-1493. PubMed ID: 38359363
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7. Discovery of u2af1 neoantigens in myeloid neoplasms.
Biernacki MA; Lok J; Black RG; Foster KA; Cummings C; Woodward KB; Monahan T; Oehler VG; Stirewalt DL; Wu D; Rongvaux A; Deeg HJ; Bleakley M
J Immunother Cancer; 2023 Dec; 11(12):. PubMed ID: 38164756
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8. Sex-associated differences in frequencies and prognostic impact of recurrent genetic alterations in adult acute myeloid leukemia (Alliance, AMLCG).
Ozga M; Nicolet D; Mrózek K; Yilmaz AS; Kohlschmidt J; Larkin KT; Blachly JS; Oakes CC; Buss J; Walker CJ; Orwick S; Jurinovic V; Rothenberg-Thurley M; Dufour A; Schneider S; Sauerland MC; Görlich D; Krug U; Berdel WE; Woermann BJ; Hiddemann W; Braess J; Subklewe M; Spiekermann K; Carroll AJ; Blum WG; Powell BL; Kolitz JE; Moore JO; Mayer RJ; Larson RA; Uy GL; Stock W; Metzeler KH; Grimes HL; Byrd JC; Salomonis N; Herold T; Mims AS; Eisfeld AK
Leukemia; 2024 Jan; 38(1):45-57. PubMed ID: 38017103
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9. u2af1 in various neoplastic diseases and relevant targeted therapies for malignant cancers with complex mutations (Review).
Nian Q; Li Y; Li J; Zhao L; Rodrigues Lima F; Zeng J; Liu R; Ye Z
Oncol Rep; 2024 Jan; 51(1):. PubMed ID: 37975232
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10. R-Loop Accumulation in Spliceosome Mutant leukemias Confers Sensitivity to PARP1 Inhibition by Triggering Transcription-Replication Conflicts.
Liu ZS; Sinha S; Bannister M; Song A; Arriaga-Gomez E; McKeeken AJ; Bonner EA; Hanson BK; Sarchi M; Takashima K; Zong D; Corral VM; Nguyen E; Yoo J; Chiraphapphaiboon W; Leibson C; McMahon MC; Rai S; Swisher EM; Sachs Z; Chatla S; Stirewalt DL; Deeg HJ; Skorski T; Papapetrou EP; Walter MJ; Graubert TA; Doulatov S; Lee SC; Nguyen HD
Cancer Res; 2024 Feb; 84(4):577-597. PubMed ID: 37967363
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11. IRAK-4 inhibition: emavusertib for the treatment of lymphoid and myeloid malignancies.
Parrondo RD; Iqbal M; Von Roemeling R; Von Roemeling C; Tun HW
Front Immunol; 2023; 14():1239082. PubMed ID: 37954584
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12. Genomic Mutation Profiles of Patients with Acute Myeloid leukemia in Korea: a Single-Center Experience.
Han E; Ryu S; Kim D; Koh EH; Byun JH; Lee DH
Clin Lab; 2023 Nov; 69(11):. PubMed ID: 37948498
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13. The clinical features and prognostic implications of PTPN11 mutation in adult patients with acute myeloid leukemia in China.
Yang J; Zhao L; Wu Y; Niu T; Gong Y; Chen X; Huang X; Liu J; Dai Y; Ma H
Cancer Med; 2023 Dec; 12(23):21111-21117. PubMed ID: 37937729
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14. Comprehensive genomic profiling reveals molecular subsets of
Johnson SM; Haberberger J; Galeotti J; Ramkissoon L; Coombs CC; Richardson DR; Foster MC; Duncan D; Montgomery ND; Ferguson NL; Zeidner JF
Leuk Lymphoma; 2024 Feb; 65(2):209-218. PubMed ID: 37921062
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15. Extreme thrombocytosis with an aggressive evolution harboring a novel variant of calreticulin (CALR) in exon 3.
Bonnet S; Carillo S; Legrand B; Burroni B; Lavabre-Bertrand T; Requirand G; Robert N; Fornero L; Al Mansoori A; Moreaux J; Cartron G; Gabellier L; Herbaux C
Eur J Haematol; 2024 Mar; 112(3):475-478. PubMed ID: 37918825
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16. Genomic alterations in blast phase of BCR::ABL1-negative myeloproliferative neoplasms.
Chen D; Weinberg OK
Int J Lab Hematol; 2023 Dec; 45(6):839-844. PubMed ID: 37867386
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17. Impact of single versus multiple spliceosome mutations on myelodysplastic syndrome.
Nagehan P; Sabbir M; Song J; Mohammad H
J Clin Exp Hematop; 2023; 63(3):173-176. PubMed ID: 37766563
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18. u2af1 pathogenic variants in myeloid neoplasms and precursor states: distribution of co-mutations and prognostic heterogeneity.
Badar T; Vanegas YAM; Nanaa A; Foran JM; Al-Kali A; Mangaonkar A; Murthy H; Alkhateeb HB; Viswanatha D; He R; Shah M; Yi CA; Litzow MR; Gangat N; Tefferi A; Patnaik MM
Blood Cancer J; 2023 Sep; 13(1):149. PubMed ID: 37735430
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19. A globally applicable "triple A" risk model for essential thrombocythemia based on Age, Absolute neutrophil count, and Absolute lymphocyte count.
Tefferi A; Loscocco GG; Farrukh F; Szuber N; Mannelli F; Pardanani A; Hanson CA; Ketterling RP; De Stefano V; Carobbio A; Barbui T; Guglielmelli P; Gangat N; Vannucchi AM
Am J Hematol; 2023 Dec; 98(12):1829-1837. PubMed ID: 37665758
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20. Myelodysplastic neoplasm-associated u2af1 mutations induce host defense defects by compromising neutrophil chemotaxis.
Gurule NJ; Malcolm KC; Harris C; Knapp JR; O'Connor BP; McClendon J; Janssen WJ; Lee FFY; Price C; Osaghae-Nosa J; Wheeler EA; McMahon CM; Pietras EM; Pollyea DA; Alper S
Leukemia; 2023 Oct; 37(10):2115-2124. PubMed ID: 37591942
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