Terms: = Leukemia AND XPO1, DKFZp686B1823, 7514, ENSG00000082898, O14980, CRM1 AND Prognosis
27 results:
1. Structural variants involving MLLT10 fusion are associated with adverse outcomes in pediatric acute myeloid leukemia.
Abla O; Ries RE; Triche T; Gerbing RB; Hirsch B; Raimondi S; Cooper T; Farrar JE; Buteyn N; Harmon LM; Wen H; Deshpande AJ; Kolb EA; Gamis AS; Aplenc R; Alonzo T; Meshinchi S
Blood Adv; 2024 Apr; 8(8):2005-2017. PubMed ID: 38306602
[TBL] [Abstract] [Full Text] [Related]
2. Chronic Lymphocytic leukemia IGHV Somatic Hypermutation Detection by Targeted Capture Next-Generation Sequencing.
Grants JM; May C; Bridgers J; Huang S; Gillis S; Meissner B; Boyle M; Ben-Neriah S; Hung S; Duns G; Hilton L; Gerrie AS; Marra M; Kridel R; Sabatini PJB; Steidl C; Scott DW; Karsan A
Clin Chem; 2024 Jan; 70(1):273-284. PubMed ID: 38175592
[TBL] [Abstract] [Full Text] [Related]
3. Azacitidine Is Synergistically Lethal with xpo1 Inhibitor Selinexor in Acute Myeloid leukemia by Targeting xpo1/eIF4E/c-MYC Signaling.
Long H; Hou Y; Li J; Song C; Ge Z
Int J Mol Sci; 2023 Apr; 24(7):. PubMed ID: 37047788
[TBL] [Abstract] [Full Text] [Related]
4. Covalent targeting the LAS1-NOL9 axis for selective treatment in NPM1 mutant acute myeloid leukemia.
Han Y; Hu A; Qu Y; Xu Q; Wang H; Feng Y; Hu Y; He L; Wu H; Wang X
Pharmacol Res; 2023 Mar; 189():106700. PubMed ID: 36796466
[TBL] [Abstract] [Full Text] [Related]
5. Prognostic value and therapeutic targeting of xpo1 in chronic lymphocytic leukemia.
Xu Z; Pan B; Miao Y; Li Y; Qin S; Liang J; Kong Y; Zhang X; Tang J; Xia Y; Zhu H; Wang L; Li J; Wu J; Xu W
Clin Exp Med; 2023 Oct; 23(6):2651-2662. PubMed ID: 36738306
[TBL] [Abstract] [Full Text] [Related]
6. Venetoclax enhances DNA damage induced by xpo1 inhibitors: A novel mechanism underlying the synergistic antileukaemic effect in acute myeloid leukaemia.
Yu H; Wu S; Liu S; Li X; Gai Y; Lin H; Wang Y; Edwards H; Ge Y; Wang G
J Cell Mol Med; 2022 May; 26(9):2646-2657. PubMed ID: 35355406
[TBL] [Abstract] [Full Text] [Related]
7. Distinct genomic landscape of Chinese pediatric acute myeloid leukemia impacts clinical risk classification.
Liu T; Rao J; Hu W; Cui B; Cai J; Liu Y; Sun H; Chen X; Tang Y; Chen J; Wang X; Wang H; Qian W; Mao B; Guo S; Wang R; Liu Y; Shen S
Nat Commun; 2022 Mar; 13(1):1640. PubMed ID: 35347147
[TBL] [Abstract] [Full Text] [Related]
8. Selective inhibition of nuclear export: a promising approach in the shifting treatment paradigms for hematological neoplasms.
Balasubramanian SK; Azmi AS; Maciejewski J
Leukemia; 2022 Mar; 36(3):601-612. PubMed ID: 35091658
[TBL] [Abstract] [Full Text] [Related]
9. Molecular regulators of HOXA9 in acute myeloid leukemia.
Aryal S; Zhang Y; Wren S; Li C; Lu R
FEBS J; 2023 Jan; 290(2):321-339. PubMed ID: 34743404
[TBL] [Abstract] [Full Text] [Related]
10. A phase I trial of selinexor plus FLAG-Ida for the treatment of refractory/relapsed adult acute myeloid leukemia patients.
Martínez Sánchez MP; Megías-Vericat JE; Rodríguez-Veiga R; Vives S; Bergua JM; Torrent A; Suárez-Varela S; Boluda B; Martínez-López J; Cano-Ferri I; Acuña-Cruz E; Torres-Miñana L; Martín-Herreros B; Serrano A; Sempere A; Barragán E; Sargas C; Sanz M; Martínez-Cuadrón D; Montesinos P;
Ann Hematol; 2021 Jun; 100(6):1497-1508. PubMed ID: 33914097
[TBL] [Abstract] [Full Text] [Related]
11. A reduced panel of eight genes (ATM, SF3B1, NOTCH1, BIRC3, xpo1, MYD88, TNFAIP3, and TP53) as an estimator of the tumor mutational burden in chronic lymphocytic leukemia.
Chauzeix J; Pastoret C; Donaty L; Gachard N; Fest T; Feuillard J; Rizzo D
Int J Lab Hematol; 2021 Aug; 43(4):683-692. PubMed ID: 33325634
[TBL] [Abstract] [Full Text] [Related]
12. xpo1 expression worsens the prognosis of unfavorable DLBCL that can be effectively targeted by selinexor in the absence of mutant p53.
Deng M; Zhang M; Xu-Monette ZY; Pham LV; Tzankov A; Visco C; Fang X; Bhagat G; Zhu F; Dybkaer K; Chiu A; Tam W; Zu Y; Hsi ED; Choi WWL; Huh J; Ponzoni M; Ferreri AJM; Møller MB; Parsons BM; van Krieken JH; Piris MA; Winter JN; Hagemeister F; Alinari L; Li Y; Andreeff M; Xu B; Young KH
J Hematol Oncol; 2020 Nov; 13(1):148. PubMed ID: 33148342
[TBL] [Abstract] [Full Text] [Related]
13. AMP-activated protein kinase activation primes cytoplasmic translocation and autophagic degradation of the BCR-ABL protein in CML cells.
Koyama D; Kikuchi J; Kuroda Y; Ohta M; Furukawa Y
Cancer Sci; 2021 Jan; 112(1):194-204. PubMed ID: 33070465
[TBL] [Abstract] [Full Text] [Related]
14. Selinexor, selective inhibitor of nuclear export: Unselective bullet for blood cancers.
Benkova K; Mihalyova J; Hajek R; Jelinek T
Blood Rev; 2021 Mar; 46():100758. PubMed ID: 32972802
[TBL] [Abstract] [Full Text] [Related]
15. A comprehensive review of genetic alterations and molecular targeted therapies for the implementation of personalized medicine in acute myeloid leukemia.
Kirtonia A; Pandya G; Sethi G; Pandey AK; Das BC; Garg M
J Mol Med (Berl); 2020 Aug; 98(8):1069-1091. PubMed ID: 32620999
[TBL] [Abstract] [Full Text] [Related]
16. 1q23.1 homozygous deletion and downregulation of Fc receptor-like family genes confer poor prognosis in chronic lymphocytic leukemia.
Daniele G; L'Abbate A; Turchiano A; Palumbo O; Carella M; Lo Cunsolo C; Iuzzolino P; Lonoce A; Hernández-Sánchez M; Minoia C; Leone P; Hernandez-Rivas JM; Storlazzi CT
Clin Exp Med; 2019 May; 19(2):261-267. PubMed ID: 30877410
[TBL] [Abstract] [Full Text] [Related]
17. Selective inhibition of nuclear export with selinexor in patients with non-Hodgkin lymphoma.
Kuruvilla J; Savona M; Baz R; Mau-Sorensen PM; Gabrail N; Garzon R; Stone R; Wang M; Savoie L; Martin P; Flinn I; Jacoby M; Unger TJ; Saint-Martin JR; Rashal T; Friedlander S; Carlson R; Kauffman M; Shacham S; Gutierrez M
Blood; 2017 Jun; 129(24):3175-3183. PubMed ID: 28468797
[TBL] [Abstract] [Full Text] [Related]
18. Targeting mantle cell lymphoma metabolism and survival through simultaneous blockade of mTOR and nuclear transporter exportin-1.
Sekihara K; Saitoh K; Han L; Ciurea S; Yamamoto S; Kikkawa M; Kazuno S; Taka H; Kaga N; Arai H; Miida T; Andreeff M; Konopleva M; Tabe Y
Oncotarget; 2017 May; 8(21):34552-34564. PubMed ID: 28388555
[TBL] [Abstract] [Full Text] [Related]
19. Complex karyotypes and KRAS and POT1 mutations impact outcome in CLL after chlorambucil-based chemotherapy or chemoimmunotherapy.
Herling CD; Klaumünzer M; Rocha CK; Altmüller J; Thiele H; Bahlo J; Kluth S; Crispatzu G; Herling M; Schiller J; Engelke A; Tausch E; Döhner H; Fischer K; Goede V; Nürnberg P; Reinhardt HC; Stilgenbauer S; Hallek M; Kreuzer KA
Blood; 2016 Jul; 128(3):395-404. PubMed ID: 27226433
[TBL] [Abstract] [Full Text] [Related]
20. Profiling of somatic mutations in acute myeloid leukemia with FLT3-ITD at diagnosis and relapse.
Garg M; Nagata Y; Kanojia D; Mayakonda A; Yoshida K; Haridas Keloth S; Zang ZJ; Okuno Y; Shiraishi Y; Chiba K; Tanaka H; Miyano S; Ding LW; Alpermann T; Sun QY; Lin DC; Chien W; Madan V; Liu LZ; Tan KT; Sampath A; Venkatesan S; Inokuchi K; Wakita S; Yamaguchi H; Chng WJ; Kham SK; Yeoh AE; Sanada M; Schiller J; Kreuzer KA; Kornblau SM; Kantarjian HM; Haferlach T; Lill M; Kuo MC; Shih LY; Blau IW; Blau O; Yang H; Ogawa S; Koeffler HP
Blood; 2015 Nov; 126(22):2491-501. PubMed ID: 26438511
[TBL] [Abstract] [Full Text] [Related]
[Next]
