BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Liver cancer AND RAC1, ENSG00000136238, 5879, MIG5, MGC111543, P63000, p21-Rac1, TC-25 AND Treatment
46 results:

  • 1. Tigecycline causes loss of cell viability mediated by mitochondrial OXPHOS and rac1 in hepatocellular carcinoma cells.
    Koch DT; Yu H; Beirith I; Schirren M; Drefs M; Liu Y; Knoblauch M; Koliogiannis D; Sheng W; De Toni EN; Bazhin AV; Renz BW; Guba MO; Werner J; Ilmer M
    J Transl Med; 2023 Dec; 21(1):876. PubMed ID: 38041179
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. LANCL1, a cell surface protein, promotes liver tumor initiation through FAM49B-rac1 axis to suppress oxidative stress.
    Huang H; Tsui YM; Ho DW; Chung CY; Sze KM; Lee E; Cheung GC; Zhang VX; Wang X; Lyu X; Ng IO
    Hepatology; 2024 Feb; 79(2):323-340. PubMed ID: 37540188
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. Identification and validation of novel signature associated with hepatocellular carcinoma prognosis using Single-cell and WGCNA analysis.
    Song H; Ge Y; Xu J; Shen R; Zhang PC; Wang GQ; Liu B
    Int J Med Sci; 2023; 20(7):870-887. PubMed ID: 37324188
    [No Abstract]    [Full Text] [Related]  

  • 4. In Silico and In Vitro Studies on the Mechanisms of Chinese Medicine Formula (Yiqi Jianpi Jiedu Formula) in the treatment of Hepatocellular Carcinoma.
    Wu Z; Kang J; Tan W; Wei C; He L; Jiang X; Peng L
    Comput Math Methods Med; 2022; 2022():8669993. PubMed ID: 36345477
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. Spiropachysine A suppresses hepatocellular carcinoma proliferation by inducing methuosis in vitro and in vivo.
    Fang Y; Zhong T; Yang L; Luo F; Li Q; Wang D; Li Q; Fan Y; Yang X
    Phytomedicine; 2022 Jul; 102():154151. PubMed ID: 35584581
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. FMRP ligand circZNF609 destabilizes rac1 mRNA to reduce metastasis in acral melanoma and cutaneous melanoma.
    Shang Q; Du H; Wu X; Guo Q; Zhang F; Gong Z; Jiao T; Guo J; Kong Y
    J Exp Clin Cancer Res; 2022 May; 41(1):170. PubMed ID: 35534866
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. Overexpressed or hyperactivated rac1 as a target to treat hepatocellular carcinoma.
    Sauzeau V; Beignet J; Vergoten G; Bailly C
    Pharmacol Res; 2022 May; 179():106220. PubMed ID: 35405309
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Macropinocytosis is an alternative pathway of cysteine acquisition and mitigates sorafenib-induced ferroptosis in hepatocellular carcinoma.
    Byun JK; Lee S; Kang GW; Lee YR; Park SY; Song IS; Yun JW; Lee J; Choi YK; Park KG
    J Exp Clin Cancer Res; 2022 Mar; 41(1):98. PubMed ID: 35287706
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Genome-wide CRISPR screen identifies synthetic lethality between DOCK1 inhibition and metformin in liver cancer.
    Feng J; Lu H; Ma W; Tian W; Lu Z; Yang H; Cai Y; Cai P; Sun Y; Zhou Z; Feng J; Deng J; Shu Y; Qu K; Jia W; Gao P; Zhang H
    Protein Cell; 2022 Nov; 13(11):825-841. PubMed ID: 35217990
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. CircRNA-ABCB10 promotes gastric cancer progression by sponging miR-1915-3p to upregulate rac1.
    Liu J; Qiu G; Wang H; Li N; Liao X
    Dig Liver Dis; 2022 Jul; 54(7):896-904. PubMed ID: 34987010
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. 33-kDa ANXA3 isoform contributes to hepatocarcinogenesis
    Guo C; Li N; Dong C; Wang L; Li Z; Liu Q; Ma Q; Greenaway FT; Tian Y; Hao L; Liu S; Sun MZ
    J Adv Res; 2021 May; 30():85-102. PubMed ID: 34026289
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. IL-37bΔ1-45 suppresses the migration and invasion of endometrial cancer cells by targeting the rac1/NF-κB/MMP2 signal pathway.
    Wang X; Wei Z; Tang Z; Xue C; Yu H; Zhang D; Li Y; Liu X; Shi Y; Zhang L; Chen G; Zhou H; Wang J; Wang X
    Lab Invest; 2021 Jun; 101(6):760-774. PubMed ID: 33753880
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Inhibition of p70 isoforms of S6K1 induces anoikis to prevent transformed human hepatocyte growth.
    Patra T; Bose SK; Kwon YC; Meyer K; Ray R
    Life Sci; 2021 Jan; 265():118764. PubMed ID: 33189822
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. DOCK6 promotes chemo- and radioresistance of gastric cancer by modulating WNT/β-catenin signaling and cancer stem cell traits.
    Chi HC; Tsai CY; Wang CS; Yang HY; Lo CH; Wang WJ; Lee KF; Lai LY; Hong JH; Chang YF; Tsai MM; Yeh CT; Wu CH; Hsieh CC; Wang LH; Chen WJ; Lin KH
    Oncogene; 2020 Sep; 39(37):5933-5949. PubMed ID: 32753649
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. PEX5, a novel target of microRNA-31-5p, increases radioresistance in hepatocellular carcinoma by activating Wnt/β-catenin signaling and homologous recombination.
    Wen J; Xiong K; Aili A; Wang H; Zhu Y; Yu Z; Yao X; Jiang P; Xue L; Wang J
    Theranostics; 2020; 10(12):5322-5340. PubMed ID: 32373215
    [No Abstract]    [Full Text] [Related]  

  • 16. Verification of EZH2 as a druggable target in metastatic uveal melanoma.
    Jin B; Zhang P; Zou H; Ye H; Wang Y; Zhang J; Yang H; Pan J
    Mol Cancer; 2020 Mar; 19(1):52. PubMed ID: 32127003
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. [Effects of arsenic trioxide on migration, invasion and apoptosis of hepatocellular carcinoma HepG2 cells].
    He J; Xu B; Gao W; Su G; Yu H; Shen Y; Liu X
    Sheng Wu Yi Xue Gong Cheng Xue Za Zhi; 2020 Feb; 37(1):105-111. PubMed ID: 32096383
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Long noncoding RNA AURKAPS1 potentiates malignant hepatocellular carcinoma progression by regulating miR-142, miR-155 and miR-182.
    Li J; Guo W; Xue W; Xu P; Deng Z; Zhang D; Zheng S; Qiu X
    Sci Rep; 2019 Dec; 9(1):19645. PubMed ID: 31873123
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Chemotherapy induced PRL3 expression promotes cancer growth via plasma membrane remodeling and specific alterations of caveolae-associated signaling.
    Csoboz B; Gombos I; Tatrai E; Tovari J; Kiss AL; Horvath I; Vigh L
    Cell Commun Signal; 2018 Aug; 16(1):51. PubMed ID: 30157875
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Annexin A5 regulates hepatocarcinoma malignancy via CRKI/II-DOCK180-rac1 integrin and MEK-ERK pathways.
    Sun X; Liu S; Wang J; Wei B; Guo C; Chen C; Sun MZ
    Cell Death Dis; 2018 May; 9(6):637. PubMed ID: 29802377
    [TBL] [Abstract] [Full Text] [Related]  


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