Terms: = Lung cancer AND PIK3CA, MGC142161, 5290, ENSG00000121879, P42336, MGC142163, p110-alpha, PI3K AND Treatment
1531 results:
1. Exploring the efficacy and molecular mechanism of Danhong injection comprehensively in the treatment of idiopathic pulmonary fibrosis by combining meta-analysis, network pharmacology, and molecular docking methods.
Wu X; Li W; Luo Z; Chen Y
Medicine (Baltimore); 2024 May; 103(19):e38133. PubMed ID: 38728523
[TBL] [Abstract] [Full Text] [Related]
2. SDF-1 promotes metastasis of NSCLC by enhancing chemoattraction of megakaryocytes through the pi3k/Akt signaling pathway.
Ai Y; Wan C; Chen Z; Wang Y; Zhao W; Huang W
J Biosci; 2024; 49():. PubMed ID: 38726826
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3. DNAJC24 acts directly with PCNA and promotes malignant progression of LUAD by activating phosphorylation of AKT.
Liu D; Zuo R; Liu W; He Y; Wang Y; Yue P; Gong W; Cui J; Zhu F; Luo Y; Qi L; Guo Y; Chen L; Li G; Liu Z; Chen P; Guo H
FASEB J; 2024 May; 38(9):e23630. PubMed ID: 38713100
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4. The combination of methionine adenosyltransferase 2A inhibitor and methyltransferase like 3 inhibitor promotes apoptosis of non-small cell lung cancer cells and produces synergistic anti-tumor activity.
Xuan YF; Lu S; Ou YJ; Bao XB; Huan XJ; Song SS; Miao ZH; Wang YQ
Biochem Biophys Res Commun; 2024 Jul; 716():150011. PubMed ID: 38704890
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5. The potential role of circular RNAs -regulated pi3k signaling in non-small cell lung cancer: Molecular insights and clinical perspective.
Kahkesh S; Khoshnazar SM; Gholinezhad Y; Esmailzadeh S; Hosseini SA; Alimohammadi M; Mafi A
Pathol Res Pract; 2024 May; 257():155316. PubMed ID: 38692125
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6. CD146 Promotes EMT-Mediated Migration and Invasion of NSCLC via pi3k/Akt Signaling Pathway.
Wei N; Wu X; Yu Y; Zhou H; Cui K; Zhao X; Zhang X
Front Biosci (Landmark Ed); 2024 Apr; 29(4):140. PubMed ID: 38682195
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7. Tumour-derived exosome SNHG17 induced by oestrogen contributes to ovarian cancer progression via the CCL13-CCR2-M2 macrophage axis.
Liang H; Geng S; Wang Y; Fang Q; Xin Y; Li Y
J Cell Mol Med; 2024 May; 28(9):e18315. PubMed ID: 38680032
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8. Curcumin Alone and Combined With pi3k Inhibitors Elicits Positive Effects on Oropharyngeal cancer Cell Lines Regardless of HPV Status.
Lukoceviciute M; Zupancic M; Kostopoulou ON; Holzhauser S; Dalianis T
Anticancer Res; 2024 May; 44(5):1863-1876. PubMed ID: 38677772
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9. Targeted inhibition of the pi3k/AKT/mTOR pathway by (+)-anthrabenzoxocinone induces cell cycle arrest, apoptosis, and autophagy in non-small cell lung cancer.
Li XQ; Cheng XJ; Wu J; Wu KF; Liu T
Cell Mol Biol Lett; 2024 Apr; 29(1):58. PubMed ID: 38649803
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10. Mobocertinib in Patients with EGFR Exon 20 Insertion-Positive Non-Small Cell lung cancer (MOON): An International Real-World Safety and Efficacy Analysis.
Illini O; Saalfeld FC; Christopoulos P; Duruisseaux M; Vikström A; Peled N; Demedts I; Dudnik E; Eisert A; Hashemi SMS; Janzic U; Kian W; Mohorcic K; Mohammed S; Silvoniemi M; Rothschild SI; Schulz C; Wesseler C; Addeo A; Armster K; Itchins M; Ivanović M; Kauffmann-Guerrero D; Koivunen J; Kuon J; Pavlakis N; Piet B; Sebastian M; Velthaus-Rusik JL; Wannesson L; Wiesweg M; Wurm R; Albers-Leischner C; Aust DE; Janning M; Fabikan H; Herold S; Klimova A; Loges S; Sharapova Y; Schütz M; Weinlinger C; Valipour A; Overbeck TR; Griesinger F; Jakopovic M; Hochmair MJ; Wermke M
Int J Mol Sci; 2024 Apr; 25(7):. PubMed ID: 38612799
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11. Suppression of NSCLC progression via the co-administration of Danusertib, an AURK inhibitor, and KRIBB11, an HSF1 inhibitor.
Zhang X; Lei Y; Chen X; He J; Liu Z; Zhu W; Xu Y; Jin X
Biochem Pharmacol; 2024 May; 223():116155. PubMed ID: 38521474
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12. TMEM158 functions as an oncogene and promotes lung adenocarcinoma progression through the pi3k/AKT pathway via interaction with TWIST1.
Xu T; Yin F; Shi K
Exp Cell Res; 2024 Apr; 437(1):114010. PubMed ID: 38508329
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13. Tyrosine phosphatase
Chen X; Keller SJ; Hafner P; Alrawashdeh AY; Avery TY; Norona J; Zhou J; Ruess DA
Front Immunol; 2024; 15():1340726. PubMed ID: 38504984
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14. Synergistic effect of cannabidiol with dasatinib on lung cancer by SRC/pi3k/AKT signal pathway.
Ye Q; Gui C; Jin D; Zhang J; Zhang J; Ma N; Xu L
Biomed Pharmacother; 2024 Apr; 173():116445. PubMed ID: 38503236
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15. Single-cell transcriptomic sequencing data reveal aberrant DNA methylation in SMAD3 promoter region in tumor-associated fibroblasts affecting molecular mechanism of radiosensitivity in non-small cell lung cancer.
Han F; Chen S; Zhang K; Zhang K; Wang M; Wang P
J Transl Med; 2024 Mar; 22(1):288. PubMed ID: 38493128
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16. Design, synthesis and mechanism study of coumarin-sulfonamide derivatives as carbonic anhydrase IX inhibitors with anticancer activity.
Lv Q; Zhang J; Cai J; Chen L; Liang J; Zhang T; Lin J; Chen R; Zhang Z; Guo P; Hong Y; Pan L; Ji H
Chem Biol Interact; 2024 Apr; 393():110947. PubMed ID: 38479716
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17. Metformin and buparlisib synergistically induce apoptosis of non-small lung cancer (NSCLC) cells via Akt/FoxO3a/Puma axis.
Shanshan W; Hongying M; Jingjing F; Rui Y
Toxicol In Vitro; 2024 May; 97():105801. PubMed ID: 38479708
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18. Activation of the pi3k/AKT signaling pathway by ARNTL2 enhances cellular glycolysis and sensitizes pancreatic adenocarcinoma to erlotinib.
Ge W; Wang Y; Quan M; Mao T; Bischof EY; Xu H; Zhang X; Li S; Yue M; Ma J; Yang H; Wang L; Yu Z; Wang L; Cui J
Mol Cancer; 2024 Mar; 23(1):48. PubMed ID: 38459558
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19. pi3kα inhibitor GNE-493 triggers antitumor immunity in murine lung cancer by inducing immunogenic cell death and activating T cells.
Xue X; Ye G; Zhang L; Zhu X; Liu Q; Rui G; Geng G; Lin Y; Chen X
Int Immunopharmacol; 2024 Mar; 130():111747. PubMed ID: 38442576
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20. pik3ca mutation as an acquired resistance driver to EGFR-TKIs in non-small cell lung cancer: Clinical challenges and opportunities.
Liu X; Mei W; Zhang P; Zeng C
Pharmacol Res; 2024 Apr; 202():107123. PubMed ID: 38432445
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