Terms: = Pancreatic cancer AND MDM2, HDM2, 4193, ENSG00000135679, HDMX, MGC71221, hdm2, Q00987 AND Treatment
41 results:
1. PELI1: key players in the oncogenic characteristics of pancreatic cancer.
Fei X; Zhu C; Liu P; Liu S; Ren L; Lu R; Hou J; Gao Y; Wang X; Pan Y
J Exp Clin Cancer Res; 2024 Mar; 43(1):91. PubMed ID: 38528516
[TBL] [Abstract] [Full Text] [Related]
2. Actinomycin D synergizes with Doxorubicin in triple-negative breast cancer by inducing P53-dependent cell apoptosis.
Yang H; Li S; Li W; Yang Y; Zhang Y; Zhang S; Hao Y; Cao W; Xu F; Wang H; Du G; Wang J
Carcinogenesis; 2024 Apr; 45(4):262-273. PubMed ID: 37997385
[TBL] [Abstract] [Full Text] [Related]
3. Molecular and Functional Heterogeneity of Primary pancreatic Neuroendocrine Tumors and Metastases.
Guo Y; Tian C; Cheng Z; Chen R; Li Y; Su F; Shi Y; Tan H
Neuroendocrinology; 2023; 113(9):943-956. PubMed ID: 37232011
[TBL] [Abstract] [Full Text] [Related]
4. miR-3,178 contributes to the therapeutic action of baicalein against hepatocellular carcinoma cells via modulating HDAC10.
Qi J; Li J; Bie B; Shi M; Zhu M; Tian J; Zhu K; Sun J; Mu Y; Li Z; Guo Y
Phytother Res; 2023 Jan; 37(1):295-309. PubMed ID: 36070933
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5. Mechanism of apoptosis activation by Curcumin rescued mutant p53Y220C in human pancreatic cancer.
Malhotra L; Sharma S; Hariprasad G; Dhingra R; Mishra V; Sharma RS; Kaur P; Ethayathulla AS
Biochim Biophys Acta Mol Cell Res; 2022 Dec; 1869(12):119343. PubMed ID: 36007676
[TBL] [Abstract] [Full Text] [Related]
6. treatment with b-AP15 to Inhibit UCHL5 and USP14 Deubiquitinating Activity and Enhance p27 and Cyclin E1 for Tumors with
Jiang ZY; Hong J; Zhang JH; Wang XF; Ma YS; Xiong ZX; Sun HR; Cheng C; Xie BZ; Liu JB; Ouyang YG; Fu D
Technol Cancer Res Treat; 2022; 21():15330338221119745. PubMed ID: 35971329
[No Abstract] [Full Text] [Related]
7. Small-Molecule MMRi62 Induces Ferroptosis and Inhibits Metastasis in pancreatic cancer via Degradation of Ferritin Heavy Chain and Mutant p53.
Li J; Lama R; Galster SL; Inigo JR; Wu J; Chandra D; Chemler SR; Wang X
Mol Cancer Ther; 2022 Apr; 21(4):535-545. PubMed ID: 35131878
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8. Kidney cancer biomarkers and targets for therapeutics: survivin (BIRC5), XIAP, MCL-1, HIF1α, HIF2α, NRF2, mdm2, MDM4, p53, KRAS and AKT in renal cell carcinoma.
Li F; Aljahdali IAM; Zhang R; Nastiuk KL; Krolewski JJ; Ling X
J Exp Clin Cancer Res; 2021 Aug; 40(1):254. PubMed ID: 34384473
[TBL] [Abstract] [Full Text] [Related]
9. Integrated multi-omics profiling of high-grade estrogen receptor-positive, HER2-negative breast cancer.
Wang K; Li L; Franch-Expósito S; Le X; Tang J; Li Q; Wu Q; Bassaganyas L; Camps J; Zhang X; Li H; Foukakis T; Xiang T; Wu J; Ren G
Mol Oncol; 2022 Jun; 16(12):2413-2431. PubMed ID: 34146382
[TBL] [Abstract] [Full Text] [Related]
10. miR-26b enhances the sensitivity of hepatocellular carcinoma to Doxorubicin via USP9X-dependent degradation of p53 and regulation of autophagy.
Chen E; Li E; Liu H; Zhou Y; Wen L; Wang J; Wang Y; Ye L; Liang T
Int J Biol Sci; 2021; 17(3):781-795. PubMed ID: 33767588
[TBL] [Abstract] [Full Text] [Related]
11. Sodium cantharidinate, a novel anti-pancreatic cancer agent that activates functional p53.
Liu X; Zhang L; Thu PM; Min W; Yang P; Li J; Li P; Xu X
Sci China Life Sci; 2021 Aug; 64(8):1295-1310. PubMed ID: 33165811
[TBL] [Abstract] [Full Text] [Related]
12. Anti-cancer Tumor Cell Necrosis of Epithelial Ovarian cancer Cell Lines Depends on High Expression of HDM-2 Protein in Their Membranes.
Thadi A; Gleeson EM; Khalili M; Shaikh MF; Goldstein E; Morano WF; Daniels LM; Grandhi N; Glatthorn H; Richard SD; Campbell PM; Sarafraz-Yazdi E; Pincus MR; Bowne WB
Ann Clin Lab Sci; 2020 Sep; 50(5):611-624. PubMed ID: 33067207
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13. Targeting Membrane HDM-2 by PNC-27 Induces Necrosis in Leukemia Cells But Not in Normal Hematopoietic Cells.
Thadi A; Lewis L; Goldstein E; Aggarwal A; Khalili M; Steele L; Polyak B; Seydafkan S; Bluth MH; Ward KA; Styler M; Campbell PM; Pincus MR; Bowne WB
Anticancer Res; 2020 Sep; 40(9):4857-4867. PubMed ID: 32878773
[TBL] [Abstract] [Full Text] [Related]
14. Holliday junction recognition protein promotes pancreatic cancer growth and metastasis via modulation of the mdm2/p53 signaling.
Wang CJ; Li X; Shi P; Ding HY; Liu YP; Li T; Lin PP; Wang YS; Zhang GQ; Cao Y
Cell Death Dis; 2020 May; 11(5):386. PubMed ID: 32439850
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15. Neddylation of sterol regulatory element-binding protein 1c is a potential therapeutic target for nonalcoholic fatty liver treatment.
Ju UI; Jeong DW; Seo J; Park JB; Park JW; Suh KS; Kim JB; Chun YS
Cell Death Dis; 2020 Apr; 11(4):283. PubMed ID: 32332706
[TBL] [Abstract] [Full Text] [Related]
16. Effects of the MDM-2 inhibitor Nutlin-3a on PDAC cells containing and lacking WT-TP53 on sensitivity to chemotherapy, signal transduction inhibitors and nutraceuticals.
Candido S; Abrams SL; Steelman LS; Lertpiriyapong K; Martelli AM; Cocco L; Ratti S; Follo MY; Murata RM; Rosalen PL; Bueno-Silva B; de Alencar SM; Lombardi P; Mao W; Montalto G; Cervello M; Rakus D; Gizak A; Lin HL; Libra M; Akula SM; McCubrey JA
Adv Biol Regul; 2019 May; 72():22-40. PubMed ID: 30898612
[TBL] [Abstract] [Full Text] [Related]
17. LUCAT1 promotes colorectal cancer tumorigenesis by targeting the ribosomal protein L40-mdm2-p53 pathway through binding with UBA52.
Zhou Q; Hou Z; Zuo S; Zhou X; Feng Y; Sun Y; Yuan X
Cancer Sci; 2019 Apr; 110(4):1194-1207. PubMed ID: 30690837
[TBL] [Abstract] [Full Text] [Related]
18. Ampullary cancer: Evaluation of somatic and germline genetic alterations and association with clinical outcomes.
Wong W; Lowery MA; Berger MF; Kemel Y; Taylor B; Zehir A; Srinivasan P; Bandlamudi C; Chou J; Capanu M; Varghese A; Yu KH; Iacobuzio-Donahue CA; Shia J; Klimstra DS; Jarnagin WR; Stadler ZK; O'Reilly EM
Cancer; 2019 May; 125(9):1441-1448. PubMed ID: 30620386
[TBL] [Abstract] [Full Text] [Related]
19. First reported case of a collision tumor composed of pancreatic adenocarcinoma and retroperitoneal liposarcoma: a case report.
Buchner D; Hieggelke L; Löser H; Bruns CJ; Quaas A; Ghadimi MPH
BMC Cancer; 2018 Dec; 18(1):1243. PubMed ID: 30541485
[TBL] [Abstract] [Full Text] [Related]
20. Bioselection Reveals miR-99b and miR-485 as Enhancers of Adenoviral Oncolysis in pancreatic cancer.
Rovira-Rigau M; Raimondi G; Marín MÁ; Gironella M; Alemany R; Fillat C
Mol Ther; 2019 Jan; 27(1):230-243. PubMed ID: 30341009
[TBL] [Abstract] [Full Text] [Related]
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