BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

Terms: = Sarcomas AND MTOR, FRAP2, FRAP1, 2475, ENSG00000198793, P42345, RAPT1, RAFT1, FRAP, FLJ44809
771 results:

  • 1. HMGA1 regulates trabectedin sensitivity in advanced soft-tissue sarcoma (STS): A Spanish Group for Research on sarcomas (GEIS) study.
    Moura DS; Mondaza-Hernandez JL; Sanchez-Bustos P; Peña-Chilet M; Cordero-Varela JA; Lopez-Alvarez M; Carrillo-Garcia J; Martin-Ruiz M; Romero-Gonzalez P; Renshaw-Calderon M; Ramos R; Marcilla D; Alvarez-Alegret R; Agra-Pujol C; Izquierdo F; Ortega-Medina L; Martin-Davila F; Hernandez-Leon CN; Romagosa C; Salgado MAV; Lavernia J; Bagué S; Mayodormo-Aranda E; Alvarez R; Valverde C; Martinez-Trufero J; Castilla-Ramirez C; Gutierrez A; Dopazo J; Hindi N; Garcia-Foncillas J; Martin-Broto J
    Cell Mol Life Sci; 2024 May; 81(1):219. PubMed ID: 38758230
    [TBL] [Abstract] [Full Text] [Related]  

  • 2. mtorC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolism.
    Levy T; Voeltzke K; Hruby L; Alasad K; Bas Z; Snaebjörnsson M; Marciano R; Scharov K; Planque M; Vriens K; Christen S; Funk CM; Hassiepen C; Kahler A; Heider B; Picard D; Lim JKM; Stefanski A; Bendrin K; Vargas-Toscano A; Kahlert UD; Stühler K; Remke M; Elkabets M; Grünewald TGP; Reichert AS; Fendt SM; Schulze A; Reifenberger G; Rotblat B; Leprivier G
    Nat Commun; 2024 May; 15(1):4083. PubMed ID: 38744825
    [TBL] [Abstract] [Full Text] [Related]  

  • 3. PI3K/mtor inhibition induces tumour microenvironment remodelling and sensitises pS6
    De Wispelaere W; Annibali D; Tuyaerts S; Messiaen J; Antoranz A; Shankar G; Dubroja N; Herreros-Pomares A; Baiden-Amissah REM; Orban MP; Delfini M; Berardi E; Van Brussel T; Schepers R; Philips G; Boeckx B; Baietti MF; Congedo L; HoWangYin KY; Bayon E; Van Rompuy AS; Leucci E; Tabruyn SP; Bosisio F; Mazzone M; Lambrechts D; Amant F
    Clin Transl Med; 2024 May; 14(5):e1655. PubMed ID: 38711203
    [TBL] [Abstract] [Full Text] [Related]  

  • 4. The complete Kaposi sarcoma-associated herpesvirus genome induces early-onset, metastatic angiosarcoma in transgenic mice.
    Sin SH; Eason AB; Kim Y; Schneider JW; Damania B; Dittmer DP
    Cell Host Microbe; 2024 May; 32(5):755-767.e4. PubMed ID: 38653242
    [TBL] [Abstract] [Full Text] [Related]  

  • 5. LncRNA NEAT1 promotes MPP+ induced injury of PC12 cells and accelerates the progression of Parkinson's disease in mice through FUS mediated inhibition of PI3K/AKT/mtor signalling pathway.
    Wang Y; Li Z; Li J; Sun C
    Exp Gerontol; 2024 Jun; 191():112436. PubMed ID: 38636570
    [TBL] [Abstract] [Full Text] [Related]  

  • 6. Acquired NF2 mutation confers resistance to TRK inhibition in an ex vivo LMNA::NTRK1-rearranged soft-tissue sarcoma cell model.
    Chen Y; Steiner S; Hagedorn C; Kollar S; Pliego-Mendieta A; Haberecker M; Plock J; Britschgi C; Planas-Paz L; Pauli C
    J Pathol; 2024 Jun; 263(2):257-269. PubMed ID: 38613194
    [TBL] [Abstract] [Full Text] [Related]  

  • 7. p53 modulates kinase inhibitor resistance and lineage plasticity in NF1-related MPNSTs.
    Grit JL; McGee LE; Tovar EA; Essenburg CJ; Wolfrum E; Beddows I; Williams K; Sheridan RTC; Schipper JL; Adams M; Arumugam M; Vander Woude T; Gurunathan S; Field JM; Wulfkuhle J; Petricoin EF; Graveel CR; Steensma MR
    Oncogene; 2024 May; 43(19):1411-1430. PubMed ID: 38480916
    [TBL] [Abstract] [Full Text] [Related]  

  • 8. Mefenamic acid exhibits antitumor activity against osteosarcoma by impeding cell growth and prompting apoptosis in human osteosarcoma cells and xenograft mice model.
    Ye J; Chang T; Zhang X; Wei D; Wang Y
    Chem Biol Interact; 2024 Apr; 393():110931. PubMed ID: 38423378
    [TBL] [Abstract] [Full Text] [Related]  

  • 9. Phase I study of sapanisertib (CB-228/TAK-228/MLN0128) in combination with ziv-aflibercept in patients with advanced solid tumors.
    Coleman N; Stephen B; Fu S; Karp D; Subbiah V; Ahnert JR; Piha-Paul SA; Wright J; Fessahaye SN; Ouyang F; Yilmaz B; Meric-Bernstam F; Naing A
    Cancer Med; 2024 Feb; 13(3):e6877. PubMed ID: 38400671
    [TBL] [Abstract] [Full Text] [Related]  

  • 10. Identifying squalene epoxidase as a metabolic vulnerability in high-risk osteosarcoma using an artificial intelligence-derived prognostic index.
    Wang Y; Ma X; Xu E; Huang Z; Yang C; Zhu K; Dong Y; Zhang C
    Clin Transl Med; 2024 Feb; 14(2):e1586. PubMed ID: 38372422
    [TBL] [Abstract] [Full Text] [Related]  

  • 11. Trifluoperazine activates AMPK / mtor / ULK1 signaling pathway to induce mitophagy in osteosarcoma cells.
    Shen W; Zeng X; Zeng X; Hu B; Ren C; Lin Z; Zhang L; Rui G; Yasen M; Chen X
    Chem Biol Interact; 2024 Apr; 392():110904. PubMed ID: 38360085
    [TBL] [Abstract] [Full Text] [Related]  

  • 12. Clinicopathological features of two ultra-rare cases of malignant perivascular epithelioid cell tumors (PEComas) involving the uterus with recent updates.
    Rekhi B; Menon S
    Indian J Pathol Microbiol; 2024; 67(1):137-140. PubMed ID: 38358203
    [TBL] [Abstract] [Full Text] [Related]  

  • 13. Conjunctival leiomyosarcoma: A clinico-pathological study with in deep molecular characterization.
    Santoro A; Angelico G; Mulè A; Minucci A; Giannuzzi F; Sammarco MG; Pagliara MM; Blasi MA
    Pathol Res Pract; 2024 Mar; 255():155182. PubMed ID: 38335782
    [TBL] [Abstract] [Full Text] [Related]  

  • 14. LncRNA RPARP-AS1 promotes the progression of osteosarcoma cells through regulating lipid metabolism.
    Cai F; Liu L; Bo Y; Yan W; Tao X; Peng Y; Zhang Z; Liao Q; Yi Y
    BMC Cancer; 2024 Feb; 24(1):166. PubMed ID: 38308235
    [TBL] [Abstract] [Full Text] [Related]  

  • 15. Enhanced Antipediatric Sarcoma Effect of Everolimus with Secukinumab by Targeting IL17A.
    Huang D; Wu Z; Wu Z; Li N; Hao L; Li K; Zeng J; Qiu B; Zhang S; Yan J
    Mol Cancer Ther; 2024 May; 23(5):721-732. PubMed ID: 38295302
    [TBL] [Abstract] [Full Text] [Related]  

  • 16. Targeting POLRMT by a first-in-class inhibitor IMT1 inhibits osteosarcoma cell growth in vitro and in vivo.
    Kong Y; Li X; Zhang H; Fu B; Jiang HY; Yang HL; Dai J
    Cell Death Dis; 2024 Jan; 15(1):57. PubMed ID: 38228583
    [TBL] [Abstract] [Full Text] [Related]  

  • 17. Lnc-PSMA8-1 activated by GEFT promotes rhabdomyosarcoma progression via upregulation of mtor expression by sponging miR-144-3p.
    Meng L; Shang H; Liu Q; Li Z; Wang X; Li Q; Li F; Zhao Z; Liu C
    BMC Cancer; 2024 Jan; 24(1):79. PubMed ID: 38225540
    [TBL] [Abstract] [Full Text] [Related]  

  • 18. Glycoprotein Nonmetastatic Melanoma Protein B (GPNMB) Immunohistochemistry Can Be a Useful Ancillary Tool to Identify Perivascular Epithelioid Cell Tumor.
    Wangsiricharoen S; Ingram DR; Morey RR; Wani K; Lazar AJ; Wang WL
    Mod Pathol; 2024 Mar; 37(3):100426. PubMed ID: 38219952
    [TBL] [Abstract] [Full Text] [Related]  

  • 19. Soy isoflavones induces mitophagy to inhibit the progression of osteosarcoma by blocking the AKT/mtor signaling pathway.
    Zheng Z; Zhao X; Yuan B; Jiang S; Yan R; Dong X; Yao Q; Liang H
    Mol Med; 2024 Jan; 30(1):5. PubMed ID: 38191316
    [TBL] [Abstract] [Full Text] [Related]  

  • 20. Solute carrier family 35 member A2 regulates mitophagy through the PI3K/AKT/mtor axis, promoting the proliferation, migration, and invasion of osteosarcoma cells.
    Luo X; Zhang J; Guo C; Jiang N; Zhang F; Jiao Q; Xu K; Yang J; Qu G; Lv XB; Zhang Z
    Gene; 2024 Mar; 898():148110. PubMed ID: 38151177
    [TBL] [Abstract] [Full Text] [Related]  


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