Terms: = Sarcomas AND PIK3CA, MGC142161, 5290, ENSG00000121879, P42336, MGC142163, p110-alpha, PI3K AND Treatment
486 results:
1. HMGA1 regulates trabectedin sensitivity in advanced soft-tissue sarcoma (STS): A Spanish Group for Research on sarcomas (GEIS) study.
Moura DS; Mondaza-Hernandez JL; Sanchez-Bustos P; Peña-Chilet M; Cordero-Varela JA; Lopez-Alvarez M; Carrillo-Garcia J; Martin-Ruiz M; Romero-Gonzalez P; Renshaw-Calderon M; Ramos R; Marcilla D; Alvarez-Alegret R; Agra-Pujol C; Izquierdo F; Ortega-Medina L; Martin-Davila F; Hernandez-Leon CN; Romagosa C; Salgado MAV; Lavernia J; Bagué S; Mayodormo-Aranda E; Alvarez R; Valverde C; Martinez-Trufero J; Castilla-Ramirez C; Gutierrez A; Dopazo J; Hindi N; Garcia-Foncillas J; Martin-Broto J
Cell Mol Life Sci; 2024 May; 81(1):219. PubMed ID: 38758230
[TBL] [Abstract] [Full Text] [Related]
2. pi3k/mTOR inhibition induces tumour microenvironment remodelling and sensitises pS6
De Wispelaere W; Annibali D; Tuyaerts S; Messiaen J; Antoranz A; Shankar G; Dubroja N; Herreros-Pomares A; Baiden-Amissah REM; Orban MP; Delfini M; Berardi E; Van Brussel T; Schepers R; Philips G; Boeckx B; Baietti MF; Congedo L; HoWangYin KY; Bayon E; Van Rompuy AS; Leucci E; Tabruyn SP; Bosisio F; Mazzone M; Lambrechts D; Amant F
Clin Transl Med; 2024 May; 14(5):e1655. PubMed ID: 38711203
[TBL] [Abstract] [Full Text] [Related]
3. Principles in the Management of Glioblastoma.
Roda D; Veiga P; Melo JB; Carreira IM; Ribeiro IP
Genes (Basel); 2024 Apr; 15(4):. PubMed ID: 38674436
[TBL] [Abstract] [Full Text] [Related]
4. LncRNA NEAT1 promotes MPP+ induced injury of PC12 cells and accelerates the progression of Parkinson's disease in mice through FUS mediated inhibition of pi3k/AKT/mTOR signalling pathway.
Wang Y; Li Z; Li J; Sun C
Exp Gerontol; 2024 Jun; 191():112436. PubMed ID: 38636570
[TBL] [Abstract] [Full Text] [Related]
5. USP3 promotes osteosarcoma progression via deubiquitinating EPHA2 and activating the pi3k/AKT signaling pathway.
Li A; Wang S; Nie J; Xiao S; Xie X; Zhang Y; Tong W; Yao G; Liu N; Dan F; Shu Z; Liu J; Liu Z; Yang F
Cell Death Dis; 2024 Mar; 15(3):235. PubMed ID: 38531846
[TBL] [Abstract] [Full Text] [Related]
6. Cucurbitacin B modulates M2 macrophage differentiation and attenuates osteosarcoma progression via pi3k/AKT pathway.
Wu H; Ma T; He M; Xie W; Wang X; Lu L; Wang H; Cui Y
Phytother Res; 2024 May; 38(5):2215-2233. PubMed ID: 38411031
[TBL] [Abstract] [Full Text] [Related]
7. Identifying squalene epoxidase as a metabolic vulnerability in high-risk osteosarcoma using an artificial intelligence-derived prognostic index.
Wang Y; Ma X; Xu E; Huang Z; Yang C; Zhu K; Dong Y; Zhang C
Clin Transl Med; 2024 Feb; 14(2):e1586. PubMed ID: 38372422
[TBL] [Abstract] [Full Text] [Related]
8. Immune characteristics of dedifferentiated retroperitoneal liposarcomas and the reliability of regional samples in evaluating their tumor immune microenvironments.
Zhou C; Li M; Ren Y; Miao F; Wang Y; Wu T; Gou X; Li W
World J Surg Oncol; 2024 Jan; 22(1):25. PubMed ID: 38254190
[TBL] [Abstract] [Full Text] [Related]
9. Effect of traditional Chinese medicine in osteosarcoma: Cross-interference of signaling pathways and potential therapeutic targets.
Liu Y; Jiang B; Li Y; Zhang X; Wang L; Yao Y; Zhu B; Shi H; Chai X; Hu X; Zhang B; Li H
Medicine (Baltimore); 2024 Jan; 103(3):e36467. PubMed ID: 38241548
[TBL] [Abstract] [Full Text] [Related]
10. Mechanism of lysine oxidase-like 1 promoting synovial inflammation mediating rheumatoid arthritis development.
Hu J; Liu X; Xu Q; Zhu M; Wang S; Quan K; Dai M; Mo F; Zhan H
Aging (Albany NY); 2024 Jan; 16(1):928-947. PubMed ID: 38217541
[TBL] [Abstract] [Full Text] [Related]
11. A study protocol for an open-label, single-arm, single-center phase I clinical study on tolerability, safety, and efficacy of dalpiciclib combined with apatinib in the treatment of patients with advanced or metastatic sarcoma.
Huang H; Zhang H; Cao B
Thorac Cancer; 2024 Feb; 15(5):427-433. PubMed ID: 38211967
[TBL] [Abstract] [Full Text] [Related]
12. Exploration of anti‑osteosarcoma activity of asiatic acid based on network pharmacology and
Pang H; Wu H; Zhan Z; Wu T; Xiang M; Wang Z; Song L; Wei B
Oncol Rep; 2024 Feb; 51(2):. PubMed ID: 38186298
[TBL] [Abstract] [Full Text] [Related]
13. Sotorasib with panitumumab in chemotherapy-refractory KRAS
Kuboki Y; Fakih M; Strickler J; Yaeger R; Masuishi T; Kim EJ; Bestvina CM; Kopetz S; Falchook GS; Langer C; Krauss J; Puri S; Cardona P; Chan E; Varrieur T; Mukundan L; Anderson A; Tran Q; Hong DS
Nat Med; 2024 Jan; 30(1):265-270. PubMed ID: 38177853
[TBL] [Abstract] [Full Text] [Related]
14. Solute carrier family 35 member A2 regulates mitophagy through the pi3k/AKT/mTOR axis, promoting the proliferation, migration, and invasion of osteosarcoma cells.
Luo X; Zhang J; Guo C; Jiang N; Zhang F; Jiao Q; Xu K; Yang J; Qu G; Lv XB; Zhang Z
Gene; 2024 Mar; 898():148110. PubMed ID: 38151177
[TBL] [Abstract] [Full Text] [Related]
15. Caulis Spatholobi extracts inhibit osteosarcoma growth and metastasis through suppression of CXCR4/pi3k/AKT signaling.
Jiang Y; Gao Y; Li X; He F; Liu Y; Wang R
J Orthop Surg Res; 2023 Dec; 18(1):985. PubMed ID: 38129870
[TBL] [Abstract] [Full Text] [Related]
16. Phase I Study of mTORC1/2 Inhibitor Sapanisertib (CB-228/TAK-228) in Combination with Metformin in Patients with mTOR/AKT/pi3k Pathway Alterations and Advanced Solid Malignancies.
Subbiah V; Coleman N; Piha-Paul SA; Tsimberidou AM; Janku F; Rodon J; Pant S; Dumbrava EEI; Fu S; Hong DS; Zhang S; Sun M; Jiang Y; Roszik J; Song J; Yuan Y; Meric-Bernstam F; Naing A
Cancer Res Commun; 2024 Feb; 4(2):378-387. PubMed ID: 38126764
[TBL] [Abstract] [Full Text] [Related]
17. Factors predictive of second-line chemotherapy in soft tissue sarcoma: An analysis of the National Genomic Profiling Database.
Mochizuki T; Ikegami M; Akiyama T
Cancer Sci; 2024 Feb; 115(2):575-588. PubMed ID: 38115234
[TBL] [Abstract] [Full Text] [Related]
18. Exploration in the Mechanism of Ginsenoside Rg5 for the treatment of Osteosarcoma by Network Pharmacology and Molecular Docking.
Liu MY; Jiang DX; Zhao X; Zhang L; Zhang Y; Liu ZD; Liu RZ; Li HJ; Rong XY; Gao YZ
Orthop Surg; 2024 Feb; 16(2):462-470. PubMed ID: 38086608
[TBL] [Abstract] [Full Text] [Related]
19. Genomic and Molecular Characteristics of Ovarian Carcinosarcoma.
Ramphal K; Hadfield MJ; Bandera CM; Hart J; Dizon DS
Am J Clin Oncol; 2023 Dec; 46(12):572-576. PubMed ID: 37986208
[TBL] [Abstract] [Full Text] [Related]
20. Blue light photobiomodulation induced apoptosis by increasing ROS level and regulating SOCS3 and PTEN/pi3k/AKT pathway in osteosarcoma cells.
Yang J; Jiang H; Fu Q; Qin H; Li Y; Liu M
J Photochem Photobiol B; 2023 Dec; 249():112814. PubMed ID: 37956614
[TBL] [Abstract] [Full Text] [Related]
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